Developmental Biology
Anti-BATF Antibody (CAB14667)
- SKU:
- CAB14667
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Developmental Biology
Description
| Antibody Name: | Anti-BATF Antibody |
| Antibody SKU: | CAB14667 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human BATF (NP_006390.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse |
| Positive Samples: | Mouse lung, Mouse liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-125 of human BATF (NP_006390.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MPHS SDSS DSSF SRSP PPGK QDSS DDVR RVQR REKN RIAA QKSR QRQT QKAD TLHL ESED LEKQ NAAL RKEI KQLT EELK YFTS VLNS HEPL CSVL AAST PSPP EVVY SAHA FHQP HVSS PRFQ P |
| Gene ID: | 10538 |
| Uniprot: | Q16520 |
| Cellular Location: | Cytoplasm, Nucleus |
| Calculated MW: | 14kDa |
| Observed MW: | 14kDa |
| Synonyms: | BATF, B-ATF, BATF1, SFA-2, SFA2 |
| Background: | The protein encoded by this gene is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events. |
| UniProt Protein Function: | BATF: a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. Functions as a negative regulator of AP-1 mediated transcription by binding to Jun proteins. Jun/B-ATF heterodimers bind DNA preferentially at the 12-O-tetradecanoylphorbol-13- acetate response element (TRE) and weaker at the cAMP responsive region (CRE), but are transcriptionally inert. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 14q24.3 Cellular Component: cytoplasm; nucleus Molecular Function:protein binding; sequence-specific DNA binding; transcription factor activity Biological Process: cytokine production; defense response to protozoan; DNA damage response, signal transduction by p53 class mediator; isotype switching; lymphoid progenitor cell differentiation; myeloid dendritic cell differentiation; response to DNA damage stimulus; T-helper 2 cell differentiation |
| NCBI Summary: | The protein encoded by this gene is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of this protein mediates dimerization with members of the Jun family of proteins. This protein is thought to be a negative regulator of AP-1/ATF transcriptional events. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q16520 |
| NCBI GenInfo Identifier: | 32171340 |
| NCBI Gene ID: | 10538 |
| NCBI Accession: | Q16520.1 |
| UniProt Related Accession: | Q16520 |
| Molecular Weight: | 14,120 Da |
| NCBI Full Name: | Basic leucine zipper transcriptional factor ATF-like |
| NCBI Synonym Full Names: | basic leucine zipper ATF-like transcription factor |
| NCBI Official Symbol: | BATF |
| NCBI Official Synonym Symbols: | SFA2; B-ATF; BATF1; SFA-2 |
| NCBI Protein Information: | basic leucine zipper transcriptional factor ATF-like |
| UniProt Protein Name: | Basic leucine zipper transcriptional factor ATF-like |
| UniProt Synonym Protein Names: | B-cell-activating transcription factor; B-ATF; SF-HT-activated gene 2 protein; SFA-2 |
| Protein Family: | Basic leucine zipper transcriptional factor |
| UniProt Gene Name: | BATF |
| UniProt Entry Name: | BATF_HUMAN |
 | Western blot analysis of extracts of various cell lines, using BATF antibody (CAB14667) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
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