Anti-B7-H3 Biotinylated Recombinant Rabbit Monoclonal Antibody (HDLA018)

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SKU:
HDLA018
Product Type:
Rabbit Monoclonal Antibody
Antibody Type:
Monoclonal Antibody
Size:
100 μg
Reactivity:
Human
Host Species:
Rabbit
Antibody Isotype:
Rabbit Igg
Clone:
DM53
Synonyms:
B7-H3, CD276, B7 homolog 3, B7H3

Description

system_update_altDatasheet
SKU:HDLA018
Size:100 µg
Clonality:Monoclonal
Clone:DM53
Synonyms:B7-H3, CD276, B7 homolog 3, B7H3
Applications:ELISA, Flow Cyt
Recommended Dilution:ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:Rabbit
Isotype:Rabbit IgG
Reactivity:Human
Purification Method:Purified from cell culture supernatant by affinity chromatography
Formulation:Powder
Buffer:1XPBS
Storage:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:Research use only
Background:The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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