Cell Biology Antibodies 16

Anti-ATRN Antibody (CAB10679)

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SKU:
CAB10679
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-ATRN Antibody
Antibody SKU:CAB10679
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 84-350 of human ATRN (NP_647538.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 84-350 of human ATRN (NP_647538.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:AAAA AAVS GSAA AEAK ECDR PCVN GGRC NPGT GQCV CPAG WVGE QCQH CGGR FRLT GSSG FVTD GPGN YKYK TKCT WLIE GQPN RIMR LRFN HFAT ECSW DHLY VYDG DSIY APLV AAFS GLIV PERD GNET VPEV VATS GYAL LHFF SDAA YNLT GFNI TYSF DMCP NNCS GRGE CKIS NSSD TVEC ECSE NWKG EACD IPHC TDNC GFPH RGIC NSSD VRGC SCFS DWQG PGCS VPVP ANQS FWTR EEYS NLKL PRAS HKAV VNG
Gene ID:8455
Uniprot:O75882
Cellular Location:Cell membrane, Secreted, Single-pass type I membrane protein
Calculated MW:133kDa/141kDa/158kDa
Observed MW:Refer to figures
Synonyms:ATRN, DPPT-L, MGCA, attractin
Background:This gene encodes both membrane-bound and secreted protein isoforms. A membrane-bound isoform exhibits sequence similarity with the mouse mahogany protein, a receptor involved in controlling obesity. A secreted isoform is involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines.
UniProt Protein Function:ATRN: Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti. Has a critical role in normal myelination in the central nervous system. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Receptor, misc.; Membrane protein, integral

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: extracellular space; integral to plasma membrane

NCBI Summary:This gene encodes both membrane-bound and secreted protein isoforms. A membrane-bound isoform exhibits sequence similarity with the mouse mahogany protein, a receptor involved in controlling obesity. A secreted isoform is involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq, Apr 2016]
UniProt Code:O75882
NCBI GenInfo Identifier:13431311
NCBI Gene ID:8455
NCBI Accession:O75882.2
UniProt Secondary Accession:O75882,O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3 Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, A8KAE5,
UniProt Related Accession:O75882
Molecular Weight:133,702 Da
NCBI Full Name:Attractin
NCBI Synonym Full Names:attractin
NCBI Official Symbol:ATRN  
NCBI Official Synonym Symbols:MGCA; DPPT-L  
NCBI Protein Information:attractin
UniProt Protein Name:Attractin
UniProt Synonym Protein Names:DPPT-L; Mahogany homolog
UniProt Gene Name:ATRN  
UniProt Entry Name:ATRN_HUMAN
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