Cell Biology Antibodies 18

Anti-ATP5G3 Antibody (CAB18278)

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SKU:
CAB18278
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:Anti-ATP5G3 Antibody
Antibody SKU:CAB18278
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide of human ATP5G3.
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:
Immunogen:A synthetic peptide of human ATP5G3.
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:518
Uniprot:P48201
Cellular Location:
Calculated MW:14kDa
Observed MW:Refer to figures
Synonyms:P3, ATP5G3
Background:This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding different proteins have been identified.
UniProt Protein Function:ATP5G3: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element. Belongs to the ATPase C chain family.
UniProt Protein Details:

Protein type:Energy Metabolism - oxidative phosphorylation; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 2q31.1

Cellular Component: mitochondrial outer membrane; mitochondrial proton-transporting ATP synthase complex

Biological Process: ATP biosynthetic process; mitochondrial ATP synthesis coupled proton transport

NCBI Summary:This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding different proteins have been identified. [provided by RefSeq, Jun 2010]
UniProt Code:P48201
NCBI GenInfo Identifier:1352048
NCBI Gene ID:518
NCBI Accession:P48201.1
UniProt Secondary Accession:P48201,Q4ZFX7, B2R4Z0, D3DPF0,
UniProt Related Accession:P48201
Molecular Weight:14,693 Da
NCBI Full Name:ATP synthase F(0) complex subunit C3, mitochondrial
NCBI Synonym Full Names:ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9)
NCBI Official Symbol:ATP5G3  
NCBI Official Synonym Symbols:P3  
NCBI Protein Information:ATP synthase F(0) complex subunit C3, mitochondrial
UniProt Protein Name:ATP synthase F(0) complex subunit C3, mitochondrial
UniProt Synonym Protein Names:ATP synthase lipid-binding protein; ATP synthase proteolipid P3; ATP synthase proton-transporting mitochondrial F(0) complex subunit C3; ATPase protein 9; ATPase subunit c
UniProt Gene Name:ATP5G3  
UniProt Entry Name:AT5G3_HUMAN
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