Signal Transduction Antibodies 1

Anti-ASIC5 Antibody (CAB10307)

(No reviews yet) Write a Review
SKU:
CAB10307
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-ASIC5 Antibody
Antibody SKU:CAB10307
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 140-330 of human ASIC5 (NP_059115.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse brain, Rat brain
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 140-330 of human ASIC5 (NP_059115.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:HLQE ITAN STGS REAT DFAA SHQN FSIV EFIR NKGF YLNN STLL DCEF FGKP CSPK DFAH VFTE YGNC FTFN HGET LQAK RKVS VSGR GLSL LFNV NQEA FTDN PALG FVDA GIIF VIHS PKKV PQFD GLGL LSPV GMHA RVTI RQVK TVHQ EYPW GECN PNIK LQNF SSYS TSGC LKEC KAQH IKKQ CGC
Gene ID:51802
Uniprot:Q9NY37
Cellular Location:Cell membrane, Multi-pass membrane protein
Calculated MW:57kDa
Observed MW:53kDa
Synonyms:ASIC5, ACCN5, HINAC, INAC
Background:This gene belongs to the amiloride-sensitive Na+ channel and degenerin (NaC/DEG) family, members of which have been identified in many animal species ranging from the nematode to human. The amiloride-sensitive Na(+) channel encoded by this gene is primarily expressed in the small intestine, however, its exact function is not known.
UniProt Protein Function:ASIC5: Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride. Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC5 subfamily.
UniProt Protein Details:

Protein type:Channel, sodium; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ion channel

Chromosomal Location of Human Ortholog: 4q32.1

Cellular Component: plasma membrane

NCBI Summary:This gene belongs to the amiloride-sensitive Na+ channel and degenerin (NaC/DEG) family, members of which have been identified in many animal species ranging from the nematode to human. The amiloride-sensitive Na(+) channel encoded by this gene is primarily expressed in the small intestine, however, its exact function is not known. [provided by RefSeq, Jul 2008]
UniProt Code:Q9NY37
NCBI GenInfo Identifier:74753059
NCBI Gene ID:51802
NCBI Accession:Q9NY37.1
UniProt Related Accession:Q9NY37
Molecular Weight:57kDa
NCBI Full Name:Acid-sensing ion channel 5
NCBI Synonym Full Names:acid sensing ion channel subunit family member 5
NCBI Official Symbol:ASIC5  
NCBI Official Synonym Symbols:INAC; ACCN5; HINAC  
NCBI Protein Information:acid-sensing ion channel 5
UniProt Protein Name:Acid-sensing ion channel 5
UniProt Synonym Protein Names:Amiloride-sensitive cation channel 5; Human intestine Na(+) channel; HINaC
Protein Family:Acid-sensing ion channel
UniProt Gene Name:ASIC5  
Anti-ASIC5 Antibody (CAB10307)Western blot analysis of extracts of various cell lines, using ASIC5 antibody (CAB10307) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
View AllClose

0 Reviews

View AllClose

Related Products