Cell Biology Antibodies 2
Anti-ARRDC3 Antibody (CAB12262)
- SKU:
- CAB12262
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-ARRDC3 Antibody |
Antibody SKU: | CAB12262 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human |
Host Species: | Rabbit |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ARRDC3 (NP_065852.1). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human |
Positive Samples: | 293T |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ARRDC3 (NP_065852.1). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | MVLG KVKS LTIS FDCL NDSN VPVY SSGD TVSG RVNL EVTG EIRV KSLK IHAR GHAK VRWT ESRN AGSN TAYT QNYT EEVE YFNH KDIL IGHE RDDD NSEE GFHT IHSG RHEY AFSF ELPQ TPLA TSFE GRHG SVRY WVKA ELHR PWLL PVKL KKEF TVFE HIDI NTPS LLSP QAGT KEKT LCCW FCTS GPIS LSAK IERK GYTP GESI QIFA EIEN CSSR MVVP KAAI YQTQ AFYA KGKM KEVK QLVA NLRG ESLS SGKT ETWN GKLL KI |
Gene ID: | 57561 |
Uniprot: | Q96B67 |
Cellular Location: | Cell membrane, Cytoplasm, Cytoplasmic side, Early endosome, Endosome, Lysosome, Peripheral membrane protein |
Calculated MW: | 46kDa |
Observed MW: | 46kDa |
Synonyms: | ARRDC3, TLIMP |
Background: |
UniProt Protein Function: | ARRDC3: Belongs to the arrestin family. |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 5q14.3 Cellular Component: endosome; plasma membrane Molecular Function:beta-3 adrenergic receptor binding; protein binding Biological Process: positive regulation of ubiquitin-protein ligase activity |
NCBI Summary: | This gene encodes a member of the arrestin family of proteins, which regulate G protein-mediated signaling. The encoded protein is thought to act as a regulator of breast cancer growth and progression by binding to a phosphorylated form of integrin beta4, a tumor-related antigen, targeting the integrin for internalization and degradation. [provided by RefSeq, Jul 2016] |
UniProt Code: | Q96B67 |
NCBI GenInfo Identifier: | 74731205 |
NCBI Gene ID: | 57561 |
NCBI Accession: | Q96B67.1 |
UniProt Secondary Accession: | Q96B67,Q9P2H1, A8K6T8, |
UniProt Related Accession: | Q96B67 |
Molecular Weight: | 46kDa |
NCBI Full Name: | Arrestin domain-containing protein 3 |
NCBI Synonym Full Names: | arrestin domain containing 3 |
NCBI Official Symbol: | ARRDC3 |
NCBI Official Synonym Symbols: | TLIMP |
NCBI Protein Information: | arrestin domain-containing protein 3 |
UniProt Protein Name: | Arrestin domain-containing protein 3 |
UniProt Synonym Protein Names: | TBP-2-like inducible membrane protein |
Protein Family: | Arrestin domain-containing protein |
UniProt Gene Name: | ARRDC3 |
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