Cell Biology Antibodies 13
Anti-ARIH1 Antibody (CAB17123)
- SKU:
- CAB17123
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Antibody Name: | Anti-ARIH1 Antibody |
Antibody SKU: | CAB17123 |
Antibody Size: | 20uL, 50uL, 100uL |
Application: | WB |
Reactivity: | Human, Mouse, Rat |
Host Species: | Rabbit |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human ARIH1 (NP_005735.2). |
Application: | WB |
Recommended Dilution: | WB 1:500 - 1:2000 |
Reactivity: | Human, Mouse, Rat |
Positive Samples: |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 400 to the C-terminus of human ARIH1 (NP_005735.2). |
Purification Method: | Affinity purification |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Isotype: | IgG |
Sequence: | ARDA QERS RAAL QRYL FYCN RYMN HMQS LRFE HKLY AQVK QKME EMQQ HNMS WIEV QFLK KAVD VLCQ CRAT LMYT YVFA FYLK KNNQ SIIF ENNQ ADLE NATE VLSG YLER DISQ DSLQ DIKQ KVQD KYRY CESR RRVL LQHV HEGY EKDL WEYI ED |
Gene ID: | 25820 |
Uniprot: | Q9Y4X5 |
Cellular Location: | |
Calculated MW: | |
Observed MW: | Refer to figures |
Synonyms: | ARIH1, ARI, HARI, HHARI, UBCH7BP |
Background: |
UniProt Protein Function: | ARIH1: E3 ubiquitin-protein ligase, which catalyzes polyubiquitination of target proteins together with ubiquitin- conjugating enzyme E2 UBE2L3. May play a role in protein translation by mediating polyubiquitination of EIF4E2, leading to its subsequent degradation. Belongs to the RBR family. Ariadne subfamily. |
UniProt Protein Details: | Protein type:Ubiquitin ligase; EC 6.3.2.-; Ubiquitin conjugating system; Ligase Chromosomal Location of Human Ortholog: 15q24 Cellular Component: cytoplasm; cytosol; ubiquitin ligase complex Molecular Function:ligase activity; protein binding; small conjugating protein ligase activity; ubiquitin conjugating enzyme binding; ubiquitin protein ligase binding; ubiquitin-protein ligase activity; zinc ion binding Biological Process: positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination; protein ubiquitination; protein ubiquitination during ubiquitin-dependent protein catabolic process; ubiquitin-dependent protein catabolic process |
UniProt Code: | Q9Y4X5 |
NCBI GenInfo Identifier: | 187761373 |
NCBI Gene ID: | 25820 |
NCBI Accession: | NP_005735.2 |
UniProt Secondary Accession: | Q9Y4X5,O76026, Q9H3T6, Q9UEN0, Q9UP39, B2R6U3, |
UniProt Related Accession: | Q9Y4X5 |
Molecular Weight: | 64,118 Da |
NCBI Full Name: | E3 ubiquitin-protein ligase ARIH1 |
NCBI Synonym Full Names: | ariadne RBR E3 ubiquitin protein ligase 1 |
NCBI Official Symbol: | ARIH1 |
NCBI Official Synonym Symbols: | ARI; HARI; HHARI; UBCH7BP |
NCBI Protein Information: | E3 ubiquitin-protein ligase ARIH1 |
UniProt Protein Name: | E3 ubiquitin-protein ligase ARIH1 |
UniProt Synonym Protein Names: | H7-AP2; HHARI; Monocyte protein 6; MOP-6; Protein ariadne-1 homolog; ARI-1; UbcH7-binding protein; UbcM4-interacting protein; Ubiquitin-conjugating enzyme E2-binding protein 1 |
Protein Family: | E3 ubiquitin-protein ligase |
UniProt Gene Name: | ARIH1 |
UniProt Entry Name: | ARI1_HUMAN |