Cell Biology Antibodies 11

Anti-ARF3 Antibody (CAB8101)

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SKU:
CAB8101
Product Type:
Antibody
Applications:
IF
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology

Description

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Antibody Name:ARF3 Rabbit Polyclonal Antibody
Antibody SKU:CAB8101
Antibody Size:20uL, 50uL, 100uL
Application:IF
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human ARF3 (NP_001650.1).
Application:IF
Recommended Dilution:IF 1:50 - 1:200
Reactivity:Human
Positive Samples:
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-181 of human ARF3 (NP_001650.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MGNI FGNL LKSL IGKK EMRI LMVG LDAA GKTT ILYK LKLG EIVT TIPT IGFN VETV EYKN ISFT VWDV GGQD KIRP LWRH YFQN TQGL IFVV DSND RERV NEAR EELM RMLA EDEL RDAV LLVF ANKQ DLPN AMNA AEIT DKLG LHSL RHRN WYIQ ATCA TSGD GLYE GLDW LANQ LKNK K
Gene ID:377
Uniprot:P61204
Cellular Location:Cytoplasm, Golgi apparatus, perinuclear region
Calculated MW:16kDa/20kDa
Observed MW:
Synonyms:ARF3
Background:ADP-ribosylation factor 3 (ARF3) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2, and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. The ARF3 gene contains five exons and four introns.
UniProt Protein Function:ARF3: GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family.
UniProt Protein Details:

Protein type:G protein, monomeric, ARF; G protein; G protein, monomeric; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: Golgi membrane

Molecular Function:GTPase activity

Biological Process: phosphatidylinositol biosynthetic process; retrograde vesicle-mediated transport, Golgi to ER

NCBI Summary:ADP-ribosylation factor 3 (ARF3) is a member of the human ARF gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6) and members of each class share a common gene organization. The ARF3 gene contains five exons and four introns. [provided by RefSeq, Jul 2008]
UniProt Code:P61204
NCBI GenInfo Identifier:47117657
NCBI Gene ID:377
NCBI Accession:P61204.2
UniProt Secondary Accession:P61204,P16587, A8K6G8, B7ZB63,
UniProt Related Accession:P61204
Molecular Weight:16,145 Da
NCBI Full Name:ADP-ribosylation factor 3
NCBI Synonym Full Names:ADP ribosylation factor 3
NCBI Official Symbol:ARF3  
NCBI Protein Information:ADP-ribosylation factor 3
UniProt Protein Name:ADP-ribosylation factor 3
Protein Family:Auxin response factor
UniProt Gene Name:ARF3  
UniProt Entry Name:ARF3_HUMAN
Anti-ARF3 Polyclonal Antibody (CAB8101)Immunofluorescence analysis of U2OS cells using ARF3 antibody (CAB8101) at dilution of 1:100. Blue: DAPI for nuclear staining.
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