Cell Biology Antibodies 12
Anti-ARC Antibody (CAB9177)
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- SKU:
- CAB9177
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-ARC Antibody |
| Antibody SKU: | CAB9177 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Human, Mouse |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ARC (NP_056008.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human, Mouse |
| Positive Samples: | HeLa, Mouse brain |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ARC (NP_056008.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MELD HRTS GGLH AYPG PRGG QVAK PNVI LQIG KCRA EMLE HVRR THRH LLAE VSKQ VERE LKGL HRSV GKLE SNLD GYVP TSDS QRWK KSIK ACLC RCQE TIAN LERW VKRE MHVW REVF YRLE RWAD RLES TGGK YPVG SESA RHTV SVGV GGPE SYCH EADG YDYT VSPY AITP PPAA GELP GQEP AEAQ QYQP WVPG EDGQ PSPG VDTQ IFED PREF |
| Gene ID: | 23237 |
| Uniprot: | Q7LC44 |
| Cellular Location: | Cell junction, Cell projection, Cytoplasm, Cytoplasmic vesicle, Endosome, acrosome, cytoskeleton, dendrite, dendritic spine, postsynaptic cell membrane, postsynaptic density, secretory vesicle, synapse |
| Calculated MW: | 45kDa |
| Observed MW: | 45kDa |
| Synonyms: | ARC, Arg3.1 |
| Background: |
| UniProt Protein Function: | ARG3.1: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration. Belongs to the ARC/ARG3.1 family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 8q24.3 Cellular Component: postsynaptic membrane; cytoplasm; postsynaptic density; plasma membrane; dendritic spine; acrosome; cell junction; endosome; actin cytoskeleton Biological Process: anterior/posterior pattern formation; cell migration; regulation of cell morphogenesis; cytoskeleton organization and biogenesis; endocytosis; learning; endoderm development; regulation of neuronal synaptic plasticity |
| UniProt Code: | Q7LC44 |
| NCBI GenInfo Identifier: | 74738627 |
| NCBI Gene ID: | 23237 |
| NCBI Accession: | Q7LC44.1 |
| UniProt Secondary Accession: | Q7LC44,Q9UJW6, Q9Y469, |
| UniProt Related Accession: | Q7LC44 |
| Molecular Weight: | 45,316 Da |
| NCBI Full Name: | Activity-regulated cytoskeleton-associated protein |
| NCBI Synonym Full Names: | activity-regulated cytoskeleton-associated protein |
| NCBI Official Symbol: | ARC |
| NCBI Official Synonym Symbols: | Arg3.1 |
| NCBI Protein Information: | activity-regulated cytoskeleton-associated protein; ARC/ARG3.1; ARC {ECO:0000312|EMBL:AAG33705.1}; activity-regulated gene 3.1 protein homolog |
| UniProt Protein Name: | Activity-regulated cytoskeleton-associated protein |
| UniProt Synonym Protein Names: | ARC/ARG3.1; Activity-regulated gene 3.1 protein homolog; Arg3.1 |
| Protein Family: | Arcelin |
| UniProt Gene Name: | ARC |
| UniProt Entry Name: | ARC_HUMAN |
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