Cell Biology Antibodies 6

Anti-AP1B1 Antibody (CAB16304)

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SKU:
CAB16304
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-AP1B1 Antibody
Antibody SKU:CAB16304
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 700-800 of human AP1B1 (NP_001118.3).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:293T, C6, Mouse liver
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 700-800 of human AP1B1 (NP_001118.3).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:SDLF DLTS GVGT LSGS YVAP KAVW LPAM KAKG LEIS GTFT RQVG SISM DLQL TNKA LQVM TDFA IQFN RNSF GLAP AAPL QVHA PLSP NQTV EISL PLST V
Gene ID:162
Uniprot:Q10567
Cellular Location:
Calculated MW:101kDa/103kDa/104kDa
Observed MW:105kDa
Synonyms:AP1B1, ADTB1, AP105A, BAM22, CLAPB2
Background:Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants.
UniProt Protein Function:Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
NCBI Summary:Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
UniProt Code:Q10567
NCBI GenInfo Identifier:260436864
NCBI Gene ID:162
NCBI Accession:NP_001159491.1
UniProt Secondary Accession:Q10567,P78436, Q20WL3, Q86X54, C9JRD1, F8WDL0,
UniProt Related Accession:Q10567
Molecular Weight:101,348 Da
NCBI Full Name:AP-1 complex subunit beta-1 isoform c
NCBI Synonym Full Names:adaptor related protein complex 1 subunit beta 1
NCBI Official Symbol:AP1B1  
NCBI Official Synonym Symbols:ADTB1; BAM22; AP105A; CLAPB2  
NCBI Protein Information:AP-1 complex subunit beta-1
UniProt Protein Name:AP-1 complex subunit beta-1
UniProt Synonym Protein Names:Adaptor protein complex AP-1 subunit beta-1; Adaptor-related protein complex 1 subunit beta-1; Beta-1-adaptin; Beta-adaptin 1; Clathrin assembly protein complex 1 beta large chain; Golgi adaptor HA1/AP1 adaptin beta subunit
Protein Family:AP-1 complex
UniProt Gene Name:AP1B1  
Anti-AP1B1 Antibody (CAB16304)Western blot analysis of extracts of various cell lines, using AP1B1 antibody (CAB16304) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5min.
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