Cell Biology Antibodies 13

Anti-ANXA9 Antibody (CAB17566)

(No reviews yet) Write a Review
SKU:
CAB17566
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-ANXA9 Antibody
Antibody SKU:CAB17566
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human ANXA9 (NP_003559.2).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human
Positive Samples:A-431, HepG2
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human ANXA9 (NP_003559.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MSVT GGKM APSL TQEI LSHL GLAS KTAA WGTL GTLR TFLN FSVD KDAQ RLLR AITG QGVD RSAI VDVL TNRS REQR QLIS RNFQ ERTQ QDLM KSLQ AALS
Gene ID:8416
Uniprot:O76027
Cellular Location:
Calculated MW:
Observed MW:37kDa
Anti-ANXA9 Antibody (CAB17566)Western blot - ANXA9 Polyclonal Antibody (CAB17566)
Synonyms:ANX31, ANXA9
Background:The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. This gene encodes a divergent member of the annexin protein family in which all four homologous type II calcium-binding sites in the conserved tetrad core contain amino acid substitutions that ablate their function. However, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact. [provided by RefSeq, Jul 2008]
UniProt Protein Function:ANXA9: a calcium/phospholipid-binding protein that may act as a low affinity receptor for acetylcholine. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.
UniProt Protein Details:

Protein type:Lipid-binding; Calcium-binding

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: cell surface; cytosol

Molecular Function:acetylcholine receptor activity; phosphatidylserine binding; phospholipid binding; protein binding; protein homodimerization activity

Biological Process: cell-cell adhesion

NCBI Summary:The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. This gene encodes a divergent member of the annexin protein family in which all four homologous type II calcium-binding sites in the conserved tetrad core contain amino acid substitutions that ablate their function. However, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact. [provided by RefSeq, Jul 2008]
UniProt Code:O76027
NCBI GenInfo Identifier:134047698
NCBI Gene ID:8416
NCBI Accession:O76027.3
UniProt Secondary Accession:O76027,Q5SZF1, Q6FI55, Q9BS00, Q9HBJ6,
UniProt Related Accession:O76027
Molecular Weight:38,364 Da
NCBI Full Name:Annexin A9
NCBI Synonym Full Names:annexin A9
NCBI Official Symbol:ANXA9  
NCBI Official Synonym Symbols:ANX31  
NCBI Protein Information:annexin A9
UniProt Protein Name:Annexin A9
UniProt Synonym Protein Names:Annexin XXXI; Annexin-31; Annexin-9; Pemphaxin
Protein Family:Annexin
UniProt Gene Name:ANXA9  
UniProt Entry Name:ANXA9_HUMAN
View AllClose

0 Reviews

View AllClose

Related Products