Signal Transduction Antibodies 2
Anti-ANO1 Antibody (CAB16540)
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- SKU:
- CAB16540
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-ANO1 Antibody |
| Antibody SKU: | CAB16540 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-210 of human ANO1 (NP_060513.5). |
| Application: | IF |
| Recommended Dilution: | IF 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-210 of human ANO1 (NP_060513.5). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | SLSV DPDA ECKY GLYF RDGR RKVD YILV YHHK RPSG NRTL VRRV QHSD TPSG ARSV KQDH PLPG KGAS LDAG SGEP PMDY HEDD KRFR REEY EGNL LEAG LELE RDED TKIH GVGF VKIH APWN VLCR EAEF LKLK MPTK KMYH INET RGLL KKIN SVLQ KITD PIQP KVA |
| Gene ID: | 55107 |
| Uniprot: | Q5XXA6 |
| Cellular Location: | Cell membrane, Cytoplasm, Multi-pass membrane protein |
| Calculated MW: | 74kDa/97kDa/114kDa |
| Observed MW: |
| Synonyms: | ANO1, DOG1, ORAOV2, TAOS2, TMEM16A |
| Background: |
| UniProt Protein Function: | ANO1: Acts as a calcium-activated chloride channel. Required for normal tracheal development. Belongs to the anoctamin family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Transporter, ion channel; Transporter; Membrane protein, integral Chromosomal Location of Human Ortholog: 11q13.3 Cellular Component: apical plasma membrane; cytoplasm; plasma membrane; external side of plasma membrane Molecular Function:protein binding; protein homodimerization activity; intracellular calcium activated chloride channel activity; protein heterodimerization activity; calcium activated cation channel activity Biological Process: regulation of membrane potential; multicellular organismal development; chloride transport; transmembrane transport; cation transport |
| UniProt Code: | Q5XXA6 |
| NCBI GenInfo Identifier: | 74708278 |
| NCBI Gene ID: | 55107 |
| NCBI Accession: | Q5XXA6.1 |
| UniProt Secondary Accession: | Q5XXA6,Q8IYY8, Q8N7V3, A8KAM3, |
| UniProt Related Accession: | Q5XXA6 |
| Molecular Weight: | |
| NCBI Full Name: | Anoctamin-1 |
| NCBI Synonym Full Names: | anoctamin 1, calcium activated chloride channel |
| NCBI Official Symbol: | ANO1 |
| NCBI Official Synonym Symbols: | DOG1; TAOS2; ORAOV2; TMEM16A |
| NCBI Protein Information: | anoctamin-1; Ca2+-activated Cl- channel; oral cancer overexpressed 2; tumor-amplified and overexpressed sequence 2; discovered on gastrointestinal stromal tumors protein 1; transmembrane protein 16A (eight membrane-spanning domains) |
| UniProt Protein Name: | Anoctamin-1 |
| UniProt Synonym Protein Names: | Discovered on gastrointestinal stromal tumors protein 1; Oral cancer overexpressed protein 2; Transmembrane protein 16A; Tumor-amplified and overexpressed sequence 2 |
| Protein Family: | Anoctamin |
| UniProt Gene Name: | ANO1 |
| UniProt Entry Name: | ANO1_HUMAN |
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