Metabolism Antibodies 1
Anti-AMPD3 Antibody (CAB13464)
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- SKU:
- CAB13464
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Metabolism
Description
| Antibody Name: | Anti-AMPD3 Antibody |
| Antibody SKU: | CAB13464 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | IF |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human AMPD3 (NP_000471.1). |
| Application: | IF |
| Recommended Dilution: | IF 1:50 - 1:200 |
| Reactivity: | Human |
| Positive Samples: |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human AMPD3 (NP_000471.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MALS SEPA EMPR QFPK LNIS EVDE QVRL LAEK VFAK VLRE EDSK DALS LFTV PEDC PIGQ KEAK EREL QKEL AEQK SVET AKRK KSFK MIRS QSLS LQMP PQQD WKGP PAAS PAMS PTTP VVTG ATSL PTPA PYAM PEFQ RVTI SGDY CAGI TLED YEQA AKSL AKAL MIRE KYAR LAYH RFPR ITSQ YLGH PRAD TAPP EEGL PDFH PPPL PQED PYCL DDAP PNLD YLVH MQGG ILFV YDNK KMLE HQEP HSLP YPDL |
| Gene ID: | 272 |
| Uniprot: | Q01432 |
| Cellular Location: | |
| Calculated MW: | 24kDa/71kDa/76kDa/88kDa/89kDa |
| Observed MW: |
| Synonyms: | AMPD3 |
| Background: | This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. |
| UniProt Protein Function: | AMP deaminase plays a critical role in energy metabolism. |
| NCBI Summary: | This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q01432 |
| NCBI GenInfo Identifier: | 399033 |
| NCBI Gene ID: | 272 |
| NCBI Accession: | Q01432.1 |
| UniProt Secondary Accession: | Q01432,A0AUX0, B7Z2S2, B7Z763, B7Z877, |
| UniProt Related Accession: | Q01432 |
| Molecular Weight: | 71,222 Da |
| NCBI Full Name: | AMP deaminase 3 |
| NCBI Synonym Full Names: | adenosine monophosphate deaminase 3 |
| NCBI Official Symbol: | AMPD3 |
| NCBI Protein Information: | AMP deaminase 3 |
| UniProt Protein Name: | AMP deaminase 3 |
| UniProt Synonym Protein Names: | AMP deaminase isoform E; Erythrocyte AMP deaminase |
| Protein Family: | AMP deaminase |
| UniProt Gene Name: | AMPD3 |
| UniProt Entry Name: | AMPD3_HUMAN |
 | Immunofluorescence analysis of HeLa cells using AMPD3 antibody (CAB13464). Blue: DAPI for nuclear staining. |
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