Name: Anti-ALOX12 Antibody (CAB14703)
Brand: Metabolism Antibodies 1
SKU: CAB14703
Availability: OutOfStock

Antibody Name:	Anti-ALOX12 Antibody
Antibody SKU:	CAB14703
Antibody Size:	20uL, 50uL, 100uL
Application:	IHC IF
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 483-663 of human ALOX12 (NP_000688.2).

Application:	IHC IF
Recommended Dilution:	IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 483-663 of human ALOX12 (NP_000688.2).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	YQRD DIVK GDPE LQAW CREI TEVG LCQA QDRG FPVS FQSQ SQLC HFLT MCVF TCTA QHAA INQG QLDW YAWV PNAP CTMR MPPP TTKE DVTM ATVM GSLP DVRQ ACLQ MAIS WHLS RRQP DMVP LGHH KEKY FSGP KPKA VLNQ FRTD LEKL EKEI TARN EQLD WPYE YLKP SCIE NSVT I
Gene ID:	239
Uniprot:	P18054
Cellular Location:	Cytoplasm, Membrane, cytosol
Calculated MW:	75kDa
Observed MW:

Synonyms:	ALOX12, 12-LOX, 12S-LOX, LOG12, 12S-type
Background:

UniProt Protein Function:	ALOX12: Oxygenase and 14,15-leukotriene A4 synthase activity. Belongs to the lipoxygenase family.
UniProt Protein Details:	Protein type:EC 1.13.11.31; Lipid Metabolism - arachidonic acid; Oxidoreductase; Apoptosis Chromosomal Location of Human Ortholog: 17p13.1 Cellular Component: cytoplasm; cytosol; membrane; sarcolemma Molecular Function:arachidonate 12-lipoxygenase activity; hepoxilin A3 synthase activity; hepoxilin-epoxide hydrolase activity; lipoxygenase activity; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; protein binding Biological Process: arachidonic acid metabolic process; cell motility; fatty acid oxidation; hepoxilin biosynthetic process; hepoxilin metabolic process; linoleic acid metabolic process; lipoxygenase pathway; negative regulation of apoptosis; positive regulation of angiogenesis; positive regulation of cell adhesion; positive regulation of cell growth; positive regulation of cell migration; positive regulation of cell proliferation
UniProt Code:	P18054
NCBI GenInfo Identifier:	125987838
NCBI Gene ID:	239
NCBI Accession:	P18054.4
UniProt Secondary Accession:	P18054,O95569, Q6ISF8, Q9UQM4,
UniProt Related Accession:	P18054
Molecular Weight:	75,694 Da
NCBI Full Name:	Arachidonate 12-lipoxygenase, 12S-type
NCBI Synonym Full Names:	arachidonate 12-lipoxygenase, 12S type
NCBI Official Symbol:	ALOX12
NCBI Official Synonym Symbols:	LOG12; 12-LOX; 12S-LOX
NCBI Protein Information:	arachidonate 12-lipoxygenase, 12S-type
UniProt Protein Name:	Arachidonate 12-lipoxygenase, 12S-type
UniProt Synonym Protein Names:	Lipoxin synthase 12-LO (EC:3.3.2.-); Platelet-type lipoxygenase 12
Protein Family:	Arachidonate 12-lipoxygenase
UniProt Gene Name:	ALOX12
UniProt Entry Name:	LOX12_HUMAN

	Immunohistochemistry of paraffin-embedded rat heart using ALOX12 antibody (CAB14703) at dilution of 1:100 (40x lens).
	Immunohistochemistry of paraffin-embedded human colon carcinoma using ALOX12 antibody (CAB14703) at dilution of 1:100 (40x lens).
	Immunohistochemistry of paraffin-embedded mouse brain using ALOX12 antibody (CAB14703) at dilution of 1:100 (40x lens).
	Immunofluorescence analysis of rat lung using ALOX12 Polyclonal Antibody (CAB14703) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.