Metabolism Antibodies 1

Anti-ALDOC Antibody (CAB11618)

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SKU:
CAB11618
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism

Description

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Antibody Name:Anti-ALDOC Antibody
Antibody SKU:CAB11618
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human ALDOC (NP_005156.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:U-87MG, LO2, Mouse brain, Mouse kidney, Rat brain, Rat spinal cord
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human ALDOC (NP_005156.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MPHS YPAL SAEQ KKEL SDIA LRIV APGK GILA ADES VGSM AKRL SQIG VENT EENR RLYR QVLF SADD RVKK CIGG VIFF HETL YQKD DNGV PFVR TIQD KGIV VGIK VDKG VVPL AGTD GETT TQGL DGLS ERCA QYKK DGAD FAKW RCVL KISE RTPS ALAI LENA NV
Gene ID:230
Uniprot:P09972
Cellular Location:
Calculated MW:39kDa
Observed MW:39kDa
Synonyms:ALDOC, ALDC
Background:This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1, 6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.
UniProt Protein Function:ALDOC: a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]
UniProt Protein Details:

Protein type:EC 4.1.2.13; Lyase; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pentose phosphate pathway; Carbohydrate Metabolism - fructose and mannose

Chromosomal Location of Human Ortholog: 17cen-q12

Cellular Component: cytoskeleton; cytosol

Molecular Function:cytoskeletal protein binding; fructose-bisphosphate aldolase activity; protein binding

Biological Process: epithelial cell differentiation; fructose 1,6-bisphosphate metabolic process; fructose metabolic process; gluconeogenesis

NCBI Summary:This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]
UniProt Code:P09972
NCBI GenInfo Identifier:113613
NCBI Gene ID:230
NCBI Accession:P09972.2
UniProt Secondary Accession:P09972,Q3SYL3, Q6FH94, Q6P0L5, B2R5R3,
UniProt Related Accession:P09972
Molecular Weight:39,456 Da
NCBI Full Name:Fructose-bisphosphate aldolase C
NCBI Synonym Full Names:aldolase, fructose-bisphosphate C
NCBI Official Symbol:ALDOC  
NCBI Official Synonym Symbols:ALDC  
NCBI Protein Information:fructose-bisphosphate aldolase C
UniProt Protein Name:Fructose-bisphosphate aldolase C
UniProt Synonym Protein Names:Brain-type aldolase
Protein Family:Fructose-bisphosphate aldolase
UniProt Gene Name:ALDOC  
UniProt Entry Name:ALDOC_HUMAN
Anti-ALDOC Antibody (CAB11618)Western blot analysis of extracts of various cell lines, using ALDOC Antibody (CAB11618) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 3s.
Anti-ALDOC Antibody (CAB11618)Immunohistochemistry of paraffin-embedded mouse brain using ALDOC Rabbit pAb (CAB11618) at dilution of 1:100 (40x lens).
Anti-ALDOC Antibody (CAB11618)Immunofluorescence analysis of C6 cells using ALDOC Rabbit pAb (CAB11618) at dilution of 1:100. Blue: DAPI for nuclear staining.
Anti-ALDOC Antibody (CAB11618)Immunofluorescence analysis of NIH/3T3 cells using ALDOC Rabbit pAb (CAB11618) at dilution of 1:100. Blue: DAPI for nuclear staining.
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