Signal Transduction Antibodies 1

Anti-ALDH3B2 Antibody (CAB14702)

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SKU:
CAB14702
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction

Description

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Antibody Name:Anti-ALDH3B2 Antibody
Antibody SKU:CAB14702
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 296-385 of human ALDH3B2 (NP_000686.2).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Rat
Positive Samples:HepG2, NCI-H460
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 296-385 of human ALDH3B2 (NP_000686.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MLER TSSG SFGG NEGF TYIS LLSV PFGG VGHS GMGR YHGK FTFD TFSH HRTC LLAP SGLE KLKE IHYP PYTD WNQQ LLRW GMGS QSCT LL
Gene ID:222
Uniprot:P48448
Cellular Location:
Calculated MW:42kDa
Observed MW:48KDa
Synonyms:ALDH3B2, ALDH8
Background:This gene encodes a member of the aldehyde dehydrogenase family, a group of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene of this particular family member is over 10 kb in length. The expression of these transcripts is restricted to the salivary gland among the human tissues examined. Alternate transcriptional splice variants have been characterized.
UniProt Protein Function:Oxidizes medium and long chain aldehydes into non-toxic fatty acids.
NCBI Summary:This gene encodes a member of the aldehyde dehydrogenase family, a group of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The gene of this particular family member is over 10 kb in length. Altered methylation patterns at this locus have been observed in spermatozoa derived from patients exhibiting reduced fecundity. [provided by RefSeq, Aug 2017]
UniProt Code:P48448
NCBI GenInfo Identifier:288558849
NCBI Gene ID:222
NCBI Accession:P48448.3
UniProt Secondary Accession:P48448,Q53Y98, Q8NAL5, Q96IB2,
UniProt Related Accession:P48448
Molecular Weight:42
NCBI Full Name:Aldehyde dehydrogenase family 3 member B2
NCBI Synonym Full Names:aldehyde dehydrogenase 3 family member B2
NCBI Official Symbol:ALDH3B2  
NCBI Official Synonym Symbols:ALDH8  
NCBI Protein Information:aldehyde dehydrogenase family 3 member B2
UniProt Protein Name:Aldehyde dehydrogenase family 3 member B2
UniProt Synonym Protein Names:Aldehyde dehydrogenase 8
UniProt Gene Name:ALDH3B2  
Anti-ALDH3B2 Antibody (CAB14702)Western blot analysis of extracts of various cell lines, using ALDH3B2 antibody (CAB14702) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
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