Cell Biology Antibodies 14

AKR1B1 Rabbit Polyclonal Antibody (CAB1684)

(No reviews yet) Write a Review
SKU:
CAB1684
Product Type:
Antibody
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
Reactivity:
Human, Mouse, Rat
Synonyms:
AR, ADR, ALR2, ALDR1, AKR1B1
Research Use:
Cell Biology
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

AKR1B1 Antibody (CAB1684)

The AKR1B1 Antibody (CAB1684) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit polyclonal antibody is highly specific and reacts strongly with human samples, making it ideal for use in Western blot applications.AKR1B1 is a key enzyme in the polyol pathway, which plays a role in diabetic complications, cancer, and inflammatory processes.

This antibody is validated for use in WB, IF/ICC, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:AKR1B1 Antibody
SKU:CAB1684
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MASR LLLN NGAK MPIL GLGT WKSP PGQV TEAV KVAI DVGY RHID CAHV YQNE NEVG VAIQ EKLR EQVV KREE LFIV SKLW CTYH EKGL VKGA CQKT LSDL KLDY LDLY LIHW PTGF KPGK EFFP LDES GNVV PSDT NILD TWAA MEEL VDEG LVKA IGIS NFNH LQVE MILN KPGL KYKP AVNQ IECH PYLT QEKL IQYC QSKG IVVT AYSP LGSP DRPW AKPE DPSL LEDP RIKA IAAK HNKT TAQV LIRF PMQR NLVV IPKS VTPE RIAE NFKV FDFE LSSQ DMTT LLSY NRNW RVCA LLSC TSHK DYPF HEEF
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:
WB1:500 - 1:5000
IF/ICC1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:AR, ADR, ALR2, ALDR1, AKR1B1
Positive Sample:U-251MG, 293T, Raji, Mouse kidney, Rat testis, Rat skeletal muscle, Rat kidney
Cellular Localization:Cytoplasm.
Calculated MW:36kDa
Observed MW:36kDa

This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.

Purification MethodAffinity purification
Gene ID231
RRIDAB_2763737
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using AKR1B1 Rabbit pAb (CAB1684) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 1s.
Product ImageImmunofluorescence analysis of HeLa cells using AKR1B1 Rabbit pAb (CAB1684) at dilution of 1:50 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
Product ImageImmunofluorescence analysis of NIH/3T3 cells using AKR1B1 Rabbit pAb (CAB1684) at dilution of 1:50 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
Product ImageImmunofluorescence analysis of PC-12 cells using AKR1B1 Rabbit pAb (CAB1684) at dilution of 1:50 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
View AllClose

0 Reviews

View AllClose

Related Products