Signal Transduction Antibodies 2
Anti-AK5 Antibody (CAB15424)
(No reviews yet)
Write a Review
- SKU:
- CAB15424
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Description
| Antibody Name: | Anti-AK5 Antibody |
| Antibody SKU: | CAB15424 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB IHC IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-370 of human AK5 (NP_777283.1). |
| Application: | WB IHC IF |
| Recommended Dilution: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | LO2, Jurkat, Mouse liver, Rat liver |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 150-370 of human AK5 (NP_777283.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | LKIA ERYG FQYI SVGE LLRK KIHS TSSN RKWS LIAK IITT GELA PQET TITE IKQK LMQI PDEE GIVI DGFP RDVA QALS FEDQ ICTP DLVV FLAC ANQR LKER LLKR AEQQ GRPD DNVK ATQR RLMN FKQN AAPL VKYF QEKG LIMT FDAD RDED EVFY DISM AVDN KLFP NKEA AAGS SDLD PSMI LDTG EIID TGSD YEDQ GDDQ LNVF GEDT MGGF M |
| Gene ID: | 26289 |
| Uniprot: | Q9Y6K8 |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 21kDa/60kDa/63kDa |
| Observed MW: | 63kDa |
| Synonyms: | AK5, AK6 |
| Background: | This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. |
| UniProt Protein Function: | AK5: Active on AMP and dAMP with ATP as a donor. When GTP is used as phosphate donor, the enzyme phosphorylates AMP, CMP, and to a small extent dCMP. Belongs to the adenylate kinase family. 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Kinase, other; Nucleotide Metabolism - purine; EC 2.7.4.6; EC 2.7.4.3 Chromosomal Location of Human Ortholog: 1p31 Cellular Component: cytoplasm; cytosol; microtubule organizing center Molecular Function:nucleoside diphosphate kinase activity; nucleoside kinase activity Biological Process: ADP biosynthetic process; dADP biosynthetic process; nucleobase, nucleoside and nucleotide interconversion; nucleoside diphosphate phosphorylation; nucleoside triphosphate biosynthetic process; pyrimidine ribonucleotide biosynthetic process |
| NCBI Summary: | This gene encodes a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. This member is related to the UMP/CMP kinase of several species. It is located in the cytosol and expressed exclusively in brain. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y6K8 |
| NCBI GenInfo Identifier: | 257051028 |
| NCBI Gene ID: | 26289 |
| NCBI Accession: | Q9Y6K8.2 |
| UniProt Secondary Accession: | Q9Y6K8,Q5U622, Q6FH66, Q7Z4T5, Q86YS0, Q8N464, Q96EC9 |
| UniProt Related Accession: | Q9Y6K8 |
| Molecular Weight: | 60,315 Da |
| NCBI Full Name: | Adenylate kinase isoenzyme 5 |
| NCBI Synonym Full Names: | adenylate kinase 5 |
| NCBI Official Symbol: | AK5 |
| NCBI Official Synonym Symbols: | AK6 |
| NCBI Protein Information: | adenylate kinase isoenzyme 5 |
| UniProt Protein Name: | Adenylate kinase isoenzyme 5 |
| UniProt Synonym Protein Names: | ATP-AMP transphosphorylase 5 |
| Protein Family: | Adenylate kinase |
| UniProt Gene Name: | AK5 |
| UniProt Entry Name: | KAD5_HUMAN |
 | Western blot analysis of extracts of various cell lines, using AK5 antibody (CAB15424) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 10s. |
 | Immunohistochemistry of paraffin-embedded rat brain using AK5 antibody (CAB15424) at dilution of 1:100 (40x lens). |
View AllClose
Related Products
Human AK5 Recombinant Protein (RPPB2434)
Enzymes Recombinant Proteins
system_update_altDatasheetsystem_update_altMSDS
