Cell Biology Antibodies 2

Anti-AGRB2 Antibody (CAB12380)

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SKU:
CAB12380
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-AGRB2 Antibody
Antibody SKU:CAB12380
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 700-800 of human AGRB2 (NP_001281264.1).
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Mouse, Rat
Positive Samples:Mouse brain, Rat brain
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 700-800 of human AGRB2 (NP_001281264.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:DFIH LVGD ALKA FQSS LIVT DNLV ISIQ REPV SAVS SDIT FPMR GRRG MKDW VRHS EDRL FLPK EVLS LSSP GKPA TSGA AGSP GRGR GPGT VPPG PGHS H
Gene ID:576
Uniprot:O60241
Cellular Location:Cell membrane, Multi-pass membrane protein
Calculated MW:169kDa/171kDa/172kDa
Observed MW:173kDa
Synonyms:ADGRB2, BAI2, AGRB2
Background:This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature peptide may be further cleaved into additional products (PMID:20367554). Alternative splicing results in multiple transcript variants.
UniProt Protein Function:BAI2: Might be involved in angiogenesis inhibition. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 4 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 1p35.2

NCBI Summary:This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature peptide may be further cleaved into additional products (PMID:20367554). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
UniProt Code:O60241
NCBI GenInfo Identifier:229462818
NCBI Gene ID:576
NCBI Accession:O60241.2
UniProt Secondary Accession:O60241,Q5T6K0, Q8NGW8, Q96GZ9, B9EGK9,
UniProt Related Accession:O60241
Molecular Weight:173kDa
NCBI Full Name:Adhesion G protein-coupled receptor B2
NCBI Synonym Full Names:adhesion G protein-coupled receptor B2
NCBI Official Symbol:ADGRB2  
NCBI Official Synonym Symbols:BAI2  
NCBI Protein Information:adhesion G protein-coupled receptor B2
UniProt Protein Name:Adhesion G protein-coupled receptor B2
UniProt Synonym Protein Names:Brain-specific angiogenesis inhibitor 2
UniProt Gene Name:ADGRB2  
Anti-AGRB2 Antibody (CAB12380)Western blot analysis of extracts of various cell lines, using AGRB2 antibody (CAB12380) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
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