Cell Biology Antibodies 2
Anti-AGRB2 Antibody (CAB12380)
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- SKU:
- CAB12380
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
| Antibody Name: | Anti-AGRB2 Antibody |
| Antibody SKU: | CAB12380 |
| Antibody Size: | 20uL, 50uL, 100uL |
| Application: | WB |
| Reactivity: | Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 700-800 of human AGRB2 (NP_001281264.1). |
| Application: | WB |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Mouse, Rat |
| Positive Samples: | Mouse brain, Rat brain |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 700-800 of human AGRB2 (NP_001281264.1). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | DFIH LVGD ALKA FQSS LIVT DNLV ISIQ REPV SAVS SDIT FPMR GRRG MKDW VRHS EDRL FLPK EVLS LSSP GKPA TSGA AGSP GRGR GPGT VPPG PGHS H |
| Gene ID: | 576 |
| Uniprot: | O60241 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 169kDa/171kDa/172kDa |
| Observed MW: | 173kDa |
| Synonyms: | ADGRB2, BAI2, AGRB2 |
| Background: | This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature peptide may be further cleaved into additional products (PMID:20367554). Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | BAI2: Might be involved in angiogenesis inhibition. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:GPCR, family 2; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR Chromosomal Location of Human Ortholog: 1p35.2 |
| NCBI Summary: | This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature peptide may be further cleaved into additional products (PMID:20367554). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] |
| UniProt Code: | O60241 |
| NCBI GenInfo Identifier: | 229462818 |
| NCBI Gene ID: | 576 |
| NCBI Accession: | O60241.2 |
| UniProt Secondary Accession: | O60241,Q5T6K0, Q8NGW8, Q96GZ9, B9EGK9, |
| UniProt Related Accession: | O60241 |
| Molecular Weight: | 173kDa |
| NCBI Full Name: | Adhesion G protein-coupled receptor B2 |
| NCBI Synonym Full Names: | adhesion G protein-coupled receptor B2 |
| NCBI Official Symbol: | ADGRB2 |
| NCBI Official Synonym Symbols: | BAI2 |
| NCBI Protein Information: | adhesion G protein-coupled receptor B2 |
| UniProt Protein Name: | Adhesion G protein-coupled receptor B2 |
| UniProt Synonym Protein Names: | Brain-specific angiogenesis inhibitor 2 |
| UniProt Gene Name: | ADGRB2 |
 | Western blot analysis of extracts of various cell lines, using AGRB2 antibody (CAB12380) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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