Cell Biology Antibodies 14

Anti-ACSS2 Antibody (CAB12334)

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SKU:
CAB12334
Product Type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Monoclonal Antibody
Research Area:
Cell Biology

Description

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Antibody Name:Anti-ACSS2 Antibody
Antibody SKU:CAB12334
Antibody Size:20uL, 50uL, 100uL
Application:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human ACSS2
Application:WB
Recommended Dilution:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:HepG2, Mouse kidney, Rat liver
Immunogen:A synthesized peptide derived from human ACSS2
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:55902
Uniprot:Q9NR19
Cellular Location:
Calculated MW:79kDa
Observed MW:79KDa
Anti-ACSS2 AntibodyWestern blot - ACSS2 Rabbit mAb (CAB12334)
Synonyms:ACAS2, ACECS, ACS, ACSA, dJ1161H23.1
Background:This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
UniProt Protein Function:ACSS2: Activates acetate so that it can be used for lipid synthesis or for energy generation. Monomer. Belongs to the ATP-dependent AMP-binding enzyme family.
UniProt Protein Details:

Protein type:Carbohydrate Metabolism - pyruvate; Carbohydrate Metabolism - propanoate; Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 6.2.1.1; Ligase

Chromosomal Location of Human Ortholog: 20q11.22

Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle; nucleoplasm

Molecular Function:acetate-CoA ligase activity; AMP binding

Biological Process: ethanol oxidation; lipid biosynthetic process

NCBI Summary:This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
UniProt Code:Q9NR19
NCBI GenInfo Identifier:20137525
NCBI Gene ID:55902
NCBI Accession:Q9NR19.1
UniProt Secondary Accession:Q9NR19,Q5QPH2, Q5QPH3, Q8N238, Q96EL0, Q9NQP7, Q9UJ15 A6NE90,
UniProt Related Accession:Q9NR19
Molecular Weight:80,087 Da
NCBI Full Name:Acetyl-coenzyme A synthetase, cytoplasmic
NCBI Synonym Full Names:acyl-CoA synthetase short-chain family member 2
NCBI Official Symbol:ACSS2  
NCBI Official Synonym Symbols:ACS; ACSA; ACAS2; ACECS; dJ1161H23.1  
NCBI Protein Information:acetyl-coenzyme A synthetase, cytoplasmic
UniProt Protein Name:Acetyl-coenzyme A synthetase, cytoplasmic
UniProt Synonym Protein Names:Acetate--CoA ligase; Acetyl-CoA synthetase; ACS; AceCS; Acyl-CoA synthetase short-chain family member 2; Acyl-activating enzyme
Protein Family:Acetyl-coenzyme A synthetase
UniProt Gene Name:ACSS2  
UniProt Entry Name:ACSA_HUMAN
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