Name: Anti-ACSS2 Antibody (CAB12334)
Brand: Cell Biology Antibodies 14
SKU: CAB12334
Availability: OutOfStock

Antibody Name:	Anti-ACSS2 Antibody
Antibody SKU:	CAB12334
Antibody Size:	20uL, 50uL, 100uL
Application:	WB
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	A synthesized peptide derived from human ACSS2

Application:	WB
Recommended Dilution:	WB 1:500 - 1:2000
Reactivity:	Human, Mouse, Rat
Positive Samples:	HepG2, Mouse kidney, Rat liver

Immunogen:	A synthesized peptide derived from human ACSS2
Purification Method:	Affinity purification
Storage Buffer:	Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	Email for sequence
Gene ID:	55902
Uniprot:	Q9NR19
Cellular Location:
Calculated MW:	79kDa
Observed MW:	79KDa

Western blot - ACSS2 Rabbit mAb (CAB12334)

Synonyms:

ACAS2, ACECS, ACS, ACSA, dJ1161H23.1

Background:

This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]

UniProt Protein Function:	ACSS2: Activates acetate so that it can be used for lipid synthesis or for energy generation. Monomer. Belongs to the ATP-dependent AMP-binding enzyme family.
UniProt Protein Details:	Protein type:Carbohydrate Metabolism - pyruvate; Carbohydrate Metabolism - propanoate; Carbohydrate Metabolism - glycolysis and gluconeogenesis; EC 6.2.1.1; Ligase Chromosomal Location of Human Ortholog: 20q11.22 Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle; nucleoplasm Molecular Function:acetate-CoA ligase activity; AMP binding Biological Process: ethanol oxidation; lipid biosynthetic process
NCBI Summary:	This gene encodes a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2009]
UniProt Code:	Q9NR19
NCBI GenInfo Identifier:	20137525
NCBI Gene ID:	55902
NCBI Accession:	Q9NR19.1
UniProt Secondary Accession:	Q9NR19,Q5QPH2, Q5QPH3, Q8N238, Q96EL0, Q9NQP7, Q9UJ15 A6NE90,
UniProt Related Accession:	Q9NR19
Molecular Weight:	80,087 Da
NCBI Full Name:	Acetyl-coenzyme A synthetase, cytoplasmic
NCBI Synonym Full Names:	acyl-CoA synthetase short-chain family member 2
NCBI Official Symbol:	ACSS2
NCBI Official Synonym Symbols:	ACS; ACSA; ACAS2; ACECS; dJ1161H23.1
NCBI Protein Information:	acetyl-coenzyme A synthetase, cytoplasmic
UniProt Protein Name:	Acetyl-coenzyme A synthetase, cytoplasmic
UniProt Synonym Protein Names:	Acetate--CoA ligase; Acetyl-CoA synthetase; ACS; AceCS; Acyl-CoA synthetase short-chain family member 2; Acyl-activating enzyme
Protein Family:	Acetyl-coenzyme A synthetase
UniProt Gene Name:	ACSS2
UniProt Entry Name:	ACSA_HUMAN