ANGPTL3 Monoclonal Antibody [P1D10AT] (CPAB0057)

Name: ANGPTL3 Monoclonal Antibody [P1D10AT] (CPAB0057)
SKU: CPAB0057
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Cardiovascular Antibodies

Cardiovascular Antibodies

OverviewProduct Name:SPAM1 Monoclonal AntibodyProduct Code:CAB22178Reactivity:Human, Mouse, RatApplications:Western blotting, Imm

Purification Method:	ANGPTL3 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:	IgG1
Background:	Angiopoietin-like proteins ANGPTL3 and ANGPTL4 are secreted proteins mainly expressed in liver that have been demonstrated to regulate triglyceride metabolism by inhibiting the lipolysis of triglyceride-rich lipoproteins. ANGPTL3 is structurally similar to angiopoietins, which are vascular endothelial growth factors. The experimental results show that Angptl3 and Angptl4 function to regulate circulating triglyceride levels during different nutritional states and therefore play a role in lipid metabolism during feeding/fasting through differential inhibition of Lipoprotein lipase (LPL). Using deletion mutants of Angiopoietin 5 human, it was demonstrated that the N-terminal domain containing fragment - (17207) and not the C-terminal fibrinogen-like domain containing fragment - (207460) increased the plasma triglyceride levels in mice.
Synonyms:	Angiopoietin 5, ANGPT5, ANGPTL3.
Storage Buffer:	For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Product Name:	ANGPTL3 Antibody
Product Sku:	CPAB0057
Size:	5μg
Host Species:	Mouse
Immunogen:	Anti-human ANGPTL3 mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with Recombinant human ANGPTL3 amino acids 243-46 purified from Ecoli.
Clone:	P1D10AT.
Reactivity:	Human
Applications:	Western Blot, ELISA