ALDH2 Monoclonal Antibody [PAT2C10AT] (CPAB0252)
![ALDH2 Monoclonal Antibody [PAT2C10AT] (CPAB0252)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58477/63659/aldh2-monoclonal-antibody-pat2c10at-cpab0252__63021__81022.1706535025.jpg?c=1 "ALDH2 Monoclonal Antibody [PAT2C10AT] (CPAB0252)")
- SKU:
- CPAB0252
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- PAT2C10AT
- Applications:
- WB
- Applications:
- ELISA
![ALDH2 Monoclonal Antibody [PAT2C10AT] (CPAB0252)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58477/63659/aldh2-monoclonal-antibody-pat2c10at-cpab0252__63021__81022.1706535025.jpg?c=1&imbypass=on "ALDH2 Monoclonal Antibody [PAT2C10AT] (CPAB0252)")
Description
system_update_alt Datasheet
| Product Name: | ALDH2 Antibody |
| Product Sku: | CPAB0252 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human ALDH2 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human ALDH2 amino acids 18-517 purified from Ecoli. |
| Clone: | PAT2C10AT. |
| Reactivity: | Human |
| Applications: | Western Blot, ELISA |
| Purification Method: | ALDH2 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG2a |
| Background: | ALDH2 is part of the aldehyde dehydrogenase family of proteins which catalyze the chemical transformation from acetaldehyde to acetic acid. ALDH2 is the second enzyme of the major oxidative pathway of alcohol metabolism. ALDH2 has 2 major liver isoforms: cytosolic and mitochondrial, which differ by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Nearly all Caucasians have 2 major isozymes, whereas roughly 50% of Orientals have only the cytosolic isozyme, omitting the mitochondrial isozyme. The extremely higher rate of acute alcohol intoxication with Orientals compared to Caucasians is due to the fact of the absence of mitochondrial isozyme. ALDH2 has a low Km for acetaldehydes, and is localized in mitochondrial matrix. |
| Synonyms: | ALDM, ALDHI, ALDH-E2, MGC1806, ALDH2, Aldehyde dehydrogenase mitochondrial, ALDH class 2. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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