AKR1B1 Monoclonal Antibody
- SKU:
- CAB22132
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | AKR1B1 Monoclonal Antibody |
| Product Code: | CAB22132 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC55401 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:1000-1:5000, IF/ICC 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | A549, HeLa, NIH/3T3, Mouse skeletal muscle, Rat skeletal muscle, Rat heart |
| Cellular Location: | cytosol, extracellular exosome, extracellular space, nucleoplasm |
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of human AKR1B1 (NP_001619.1). |
| Sequence: | QNENE VGVAI QEKLR EQVVK REELF IVSKL WCTYH EKGLV KGACQ KTLSD LKLDY LDLYL IHWPT GFKPG KEFFP LDESG NVVPS DTNIL DTWAA MEELV D |
| Synonyms: | AR, ADR, ALR2, ALDR1 |
| Calculated MW: | 36kDa |
| Observed MW: | 36kDa |
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