Description
| Product Name: | Aim2 Polyclonal Antibody |
| Product Code: | CAB22874 |
| Reactivity: | Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Rat spleen |
| Cellular Location: | Cytoplasm, Nucleus |
Enables double-stranded DNA binding activity and identical protein binding activity. Involved in positive regulation of macromolecule metabolic process; pyroptosis; and regulation of defense response. Acts upstream of or within cellular response to interferon-beta. Located in cytoplasm. Part of AIM2 inflammasome complex. Orthologous to human AIM2 (absent in melanoma 2).
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of mouse Aim2 (NP_001013801.2). |
| Sequence: | DHLIQ SAGAA SAVTK AINIF QKLNY MHIAN ALEEK KKEAE RKLMT NTKKR GTQKV ENRSQ AENCS AASAT RSDND FKEQA ATEVC PQAKP QKKQM VAEQE A |
| Synonyms: | Gm1313, Ifi210 |
| Calculated MW: | 40kDa |
| Observed MW: | 39kDa |