Description
Product Name: | Aim2 Polyclonal Antibody |
Product Code: | CAB22874 |
Reactivity: | Rat |
Applications: | Western blotting |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Rat |
Tested Applications: | WB, ELISA |
Key Applications: | Western blotting |
Recommended Dilution: | WB 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Positive Samples: | Rat spleen |
Cellular Location: | Cytoplasm, Nucleus |
Enables double-stranded DNA binding activity and identical protein binding activity. Involved in positive regulation of macromolecule metabolic process; pyroptosis; and regulation of defense response. Acts upstream of or within cellular response to interferon-beta. Located in cytoplasm. Part of AIM2 inflammasome complex. Orthologous to human AIM2 (absent in melanoma 2).
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 50-150 of mouse Aim2 (NP_001013801.2). |
Sequence: | DHLIQ SAGAA SAVTK AINIF QKLNY MHIAN ALEEK KKEAE RKLMT NTKKR GTQKV ENRSQ AENCS AASAT RSDND FKEQA ATEVC PQAKP QKKQM VAEQE A |
Synonyms: | Gm1313, Ifi210 |
Calculated MW: | 40kDa |
Observed MW: | 39kDa |