AF/LE Purified Mouse/Human CD11b Monoclonal Antibody [M1/70](AGEL1099)

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SKU:
AGEL1099
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Applications:
FC

Description

Antibody Name:AF/LE Purified Mouse/Human CD11b Monoclonal Antibody
Antibody Code:AGEL1099
Size:500µg
Clone:M1/70
Synonyms:Integrin alpha-M,Itgam,CD11 antigen-like family member B,CR-3 alpha chain,Leukocyte adhesion receptor MO1,CD11b
Host Species:Rat
Species Reactivity:Human, Mouse
Applications:Neut, Purification, FC, IHC, IP
Concentration:1mg/mL
Isotype:IgG2a,k
Conjugation:Azide Free/Low endotoxin
Applications:Neut, Purification, FC, IHC, IP
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:PBS, PH7.2
Storage:Store at 2-8°C. Do not freeze.
Gene ID:16409,3684
Uniprot:P05555, P11215
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
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