AF/LE Purified Mouse CD3 epsilon Monoclonal Antibody [145-2C11](AGEL1314)

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SKU:
AGEL1314
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC

Description

Antibody Name:AF/LE Purified Mouse CD3ε Monoclonal Antibody
Antibody Code:AGEL1314
Size:500µg
Clone:145-2C11
Synonyms:T-cell surface glycoprotein CD3 epsilon chain,CD3E,T-cell surface antigen T3/Leu-4 epsilon chain,CD3e,CD3E,T3E
Host Species:Armenian Hamster
Species Reactivity:Mouse
Applications:Activ, Depletion, FC, WB, HC, IF, IP
Concentration:1mg/mL
Isotype:IgG2a,k
Conjugation:Azide Free/Low endotoxin
Applications:Activ, Depletion, FC, WB, HC, IF, IP
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:PBS, PH7.2
Storage:Store at 2-8°C. Do not freeze.
Gene ID:12501
Uniprot:P22646
Background:CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.
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