AF/LE Purified Human/Monkey CD154 Monoclonal Antibody [5C8](AGEL1603)

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SKU:
AGEL1603
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
NHP - Monkey
Applications:
FC

Description

Antibody Name:AF/LE Purified Human/Monkey CD154 Monoclonal Antibody
Antibody Code:AGEL1603
Size:500µg
Clone:5C8
Synonyms:CD40L, gp39, TRAP, T-BAM, TNFSF5
Host Species:Mouse
Species Reactivity:Human,Monkey
Applications:Block, FC, IP
Concentration:1mg/mL
Isotype:IgG2a,k
Conjugation:Azide Free/Low endotoxin
Applications:Block, FC, IP
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:0.2 µm filtered in PBS, pH7.2. Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg (< 0.002EU/µg) as Determined by LAL gel clotting assay. Purity is > 95% as determined by SDS-PAGE
Storage:Store at 2-8°C. Do not freeze.
Gene ID:959
Uniprot:P29965
Background:CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells.
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