AF/LE Purified Human HLA-DR Monoclonal Antibody [L243](AGEL1395)

Name: AF/LE Purified Human HLA-DR Monoclonal Antibody [L243](AGEL1395)
SKU: AGEL1395
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Antibody Name:	AF/LE Purified Human HLA-DR Monoclonal Antibody
Antibody Code:	AGEL1395
Size:	500µg
Clone:	L243
Synonyms:	HLA class II histocompatibility antigen DR alpha/ DRB1-15 beta chain,MHC class II antigen DRA,HLA-DRA1/DRB1,DRA/DRB1
Host Species:	Mouse
Species Reactivity:	Human
Applications:	Cell Sep-Neg, Block, Binding, FC, WB, IHC, IP

Concentration:	1mg/mL
Isotype:	IgG2a,k
Conjugation:	Azide Free/Low endotoxin
Applications:	Cell Sep-Neg, Block, Binding, FC, WB, IHC, IP
Recommended Dilution:	Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:	0.2 µm filtered in PBS, pH7.2. Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg (< 0.002EU/µg) as Determined by LAL gel clotting assay. Purity is > 95% as determined by SDS-PAGE
Storage:	Store at 2-8°C. Do not freeze.

Gene ID:	3122,3123
Uniprot:	P01903
Background:	HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.