AF/LE Purified Human HLA-DR Monoclonal Antibody [L243](AGEL1395)

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SKU:
AGEL1395
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Applications:
FC

Description

Antibody Name:AF/LE Purified Human HLA-DR Monoclonal Antibody
Antibody Code:AGEL1395
Size:500µg
Clone:L243
Synonyms:HLA class II histocompatibility antigen DR alpha/ DRB1-15 beta chain,MHC class II antigen DRA,HLA-DRA1/DRB1,DRA/DRB1
Host Species:Mouse
Species Reactivity:Human
Applications:Cell Sep-Neg, Block, Binding, FC, WB, IHC, IP
Concentration:1mg/mL
Isotype:IgG2a,k
Conjugation:Azide Free/Low endotoxin
Applications:Cell Sep-Neg, Block, Binding, FC, WB, IHC, IP
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:0.2 µm filtered in PBS, pH7.2. Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg (< 0.002EU/µg) as Determined by LAL gel clotting assay. Purity is > 95% as determined by SDS-PAGE
Storage:Store at 2-8°C. Do not freeze.
Gene ID:3122,3123
Uniprot:P01903
Background:HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.
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