Description
| Antibody Name: | AF/LE Purified Human CD4 Monoclonal Antibody |
| Antibody Code: | AGEL1385 |
| Size: | 500µg |
| Clone: | RPA-T4 |
| Synonyms: | T-cell surface glycoprotein CD4,CD4,T-cell surface antigen T4/Leu-3,CD4 |
| Host Species: | Mouse |
| Species Reactivity: | Human |
| Applications: | Block, FC, IHC, IF |
| Concentration: | 1mg/mL |
| Isotype: | IgG2a,k |
| Conjugation: | Azide Free/Low endotoxin |
| Applications: | Block, FC, IHC, IF |
| Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
| Storage Buffer: | PBS, PH7.2 |
| Storage: | Store at 2-8°C. Do not freeze. |
| Gene ID: | 920 |
| Uniprot: | P01730 |
| Background: | CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7). |