Description
Antibody Name: | AF/LE Purified Human CD3 Monoclonal Antibody |
Antibody Code: | AGEL0602 |
Size: | 500µg |
Clone: | OKT3 |
Synonyms: | T-cell surface glycoprotein CD3 epsilon chain,CD3E,T-cell surface antigen T3/Leu-4 epsilon chain,CD3e,CD3E,T3E |
Host Species: | Mouse |
Species Reactivity: | Human |
Applications: | Activ, Depletion, Inhibition, FC, IHC |
Concentration: | 1mg/mL |
Isotype: | IgG2a,k |
Conjugation: | Azide Free/Low endotoxin |
Applications: | Activ, Depletion, Inhibition, FC, IHC |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Storage Buffer: | PBS, PH7.2 |
Storage: | Store at 2-8°C. Do not freeze. |
Gene ID: | 916 |
Uniprot: | P07766 |
Background: | CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation. |