AF/LE Purified Anti-Mouse CD120b Antibody [TR75-54.7]

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SKU:
AGEL2165
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FCM
Applications:
Block
Reactivity:
Mouse
Host Species:
Armenian Hamster
Isotype:
Armenian Hamster IgG
Clone:
TR75-54.7
Conjugation:
None (Low endotoxin)

Description

Product Name:AF/LE Purified Anti-Mouse CD120b Antibody [TR75-54.7]
Product Code:AGEL2165
Clone No:TR75-54.7
Synonyms:Tumor necrosis factor receptor superfamily member 1B,Tnfrsf1b,Tumor necrosis factor receptor 2,TNF-R2,TNF-RII,TNFR-II,p75,p80 TNF-alpha receptor,CD120b
Reactivity:Mouse
Host Species:Armenian Hamster
Applications:FCM, Block
Isotype:Armenian Hamster IgG
Isotype Control:Low Endotoxin Purified Armenian Hamster IgG Isotype Control [PIP] (AGEL2697)
Conjugation:None (Purified antibody-Azide Free/Low endotoxin)
Form:Liquid
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Swissprot:P25119
Stability & Storage:Keep as concentrated solution. Store at 2-8°C. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Shipping:Biological ice pack at 4°C

CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.

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