Description
| Product Name: | ADIPOR1 Polyclonal Antibody |
| Product Code: | CAB21533 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human ADIPOR1 (NP_057083.2). |
| Sequence: | MSSHK GSVVA QGNGA PASNR EADTV ELAEL GPLLE EKGKR VIANP PKAEE EQTCP VPQEE EEEVR VLTLP LQAHH AMEKM EEFVY KVWEG RWRVI PYDVL PDWLK DNDYL LHGHR PPMPS FRACF KSIFR IHTET G |
| Synonyms: | CGI45, PAQR1, ACDCR1, CGI-45, TESBP1A |
| Calculated MW: | 43kDa |
| Observed MW: | Refer to figures |