ADH5/GSNOR Monoclonal Antibody
- SKU:
- CAB22527
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | ADH5/GSNOR Monoclonal Antibody |
| Product Code: | CAB22527 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC57643 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:2000-1:20000, IF/ICC 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HepG2, K-562, Mouse liver, Rat liver |
| Cellular Location: | Cytoplasm |
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-374 of human ADH5/GSNOR (NP_000662.3). |
| Sequence: | MANEV IKCKA AVAWE AGKPL SIEEI EVAPP KAHEV RIKII ATAVC HTDAY TLSGA DPEGC FPVIL GHEGA GIVES VGEGV TKLKA GDTVI PLYIP QCGEC KFCLN PKTNL CQKIR VTQGK GLMPD GTSRF TCKGK TILHY MGTST FSEYT VVADI SVAKI DPLAP LDKVC LLGCG ISTGY GAAVN TAKLE PGSVC AVFGL GGVGL AVIMG CKVAG ASRII GVDIN KDKFA RAKEF GATEC INPQD FSKPI QEVLI EMTDG GVDYS FECIG NVKVM RAALE ACHKG WGVSV VVGVA ASGEE IATRP FQLVT GRTWK GTAFG GWKSV ESVPK LVSEY MSKKI KVDEF VTHNL SFDEI NKAFE LMHSG KSIRT VVKI |
| Synonyms: | FDH, ADHX, ADH-3, AMEDS, BMFS7, FALDH, GSNOR, GSH-FDH, HEL-S-60p |
| Calculated MW: | 40kDa |
| Observed MW: | 40kDa |
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