Adh5 Antibody (PACO24775)
- SKU:
- PACO24775
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Adh5 Antibody (PACO24775) |
| Antibody SKU: | PACO24775 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Alcohol dehydrogenase class-3 protein (2-374AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Adh5 antibody at 2µg/ml Lane 1: Mouse liver tissue Lane 2: Mouse kidney tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 40 kDa Observed band size: 40 kDa . |
| Background: | Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. |
| Synonyms: | Alcohol dehydrogenase class-3 (EC 1.1.1.1) (Alcohol dehydrogenase 2) (Alcohol dehydrogenase 5) (Alcohol dehydrogenase B2) (ADH-B2) (Alcohol dehydrogenase class-III) (Glutathione-dependent formaldehyde dehydrogenase) (FALDH) (FDH) (GSH-FDH) (EC 1.1.1.-) (S-(hydroxymethyl)glutathione dehydrogenase) (EC 1.1.1.284), Adh5, Adh-2 Adh2 |
| UniProt Protein Function: | ADH5: Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.Protein type: Xenobiotic Metabolism - metabolism by cytochrome P450; Oxidoreductase; Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Amino Acid Metabolism - tyrosine; Energy Metabolism - methane; Mitochondrial; EC 1.1.1.284; EC 1.1.1.1; Lipid Metabolism - fatty acidCellular Component: mitochondrion; cytoplasm; nucleusMolecular Function: mevaldate reductase activity; protein homodimerization activity; zinc ion binding; metal ion binding; oxidoreductase activity; C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity; (R)-2-hydroxyisocaproate dehydrogenase activity; steroid dehydrogenase activity; D-arabinitol dehydrogenase (NADP+) activity; fatty acid binding; acetoin dehydrogenase activity; gluconate dehydrogenase activity; (R)-2-hydroxyglutarate dehydrogenase activity; phenylcoumaran benzylic ether reductase activity; aldo-keto reductase activity; formaldehyde dehydrogenase activity; alcohol dehydrogenase activity; arabinose reductase activity; isocitrate dehydrogenase activity; epoxide dehydrogenase activity; 3-ketoglucose-reductase activity; steroid dehydrogenase activity, acting on the CH-CH group of donors; 2-hydroxytetrahydrofuran dehydrogenase activity; S-(hydroxymethyl)glutathione dehydrogenase activity; 5-exo-hydroxycamphor dehydrogenase activity; steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; xylose reductase activityBiological Process: respiratory system process; response to nitrosative stress; ethanol catabolic process; formaldehyde catabolic process; peptidyl-cysteine S-nitrosylation; response to redox state; response to lipopolysaccharide; retinoid metabolic process; ethanol oxidation; positive regulation of blood pressure |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P28474 |
| NCBI GenInfo Identifier: | 568384738 |
| NCBI Gene ID: | 11532 |
| NCBI Accession: | NP_001275507.1 |
| UniProt Secondary Accession: | P28474,Q3TW83, Q8C662 |
| UniProt Related Accession: | P28474 |
| Molecular Weight: | 39,548 Da |
| NCBI Full Name: | alcohol dehydrogenase class-3 isoform 2 |
| NCBI Synonym Full Names: | alcohol dehydrogenase 5 (class III), chi polypeptide |
| NCBI Official Symbol: | Adh5 |
| NCBI Official Synonym Symbols: | Adh3; Adh-5; GSNOR |
| NCBI Protein Information: | alcohol dehydrogenase class-3; FDH; FALDH; ADH-B2; GSH-FDH; alcohol dehydrogenase 2; alcohol dehydrogenase B2; S-nitrosoglutathione reductase; alcohol dehydrogenase class-III; S-(hydroxymethyl)glutathione dehydrogenase; glutathione-dependent formaldehyde dehydrogenase |
| UniProt Protein Name: | Alcohol dehydrogenase class-3 |
| UniProt Synonym Protein Names: | Alcohol dehydrogenase 2; Alcohol dehydrogenase 5; Alcohol dehydrogenase B2; ADH-B2; Alcohol dehydrogenase class-III; Glutathione-dependent formaldehyde dehydrogenase (EC:1.1.1.-); FALDH; FDH; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase (EC:1.1.1.284) |
| Protein Family: | Alcohol dehydrogenase |
| UniProt Gene Name: | Adh5 |
| UniProt Entry Name: | ADHX_MOUSE |
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