ACTN1 Monoclonal Antibody [PAT1D10AT] (CPAB0641)
![ACTN1 Monoclonal Antibody [PAT1D10AT] (CPAB0641)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58861/64043/actn1-monoclonal-antibody-pat1d10at-cpab0641__73530__74317.1706535240.jpg?c=1 "ACTN1 Monoclonal Antibody [PAT1D10AT] (CPAB0641)")
- SKU:
- CPAB0641
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- PAT1D10AT
- Applications:
- WB
- Applications:
- ELISA
- Applications:
- FC
![ACTN1 Monoclonal Antibody [PAT1D10AT] (CPAB0641)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58861/64043/actn1-monoclonal-antibody-pat1d10at-cpab0641__73530__74317.1706535240.jpg?c=1&imbypass=on "ACTN1 Monoclonal Antibody [PAT1D10AT] (CPAB0641)")
Description
system_update_alt Datasheet
| Product Name: | ACTN1 Antibody |
| Product Sku: | CPAB0641 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human ACTN1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ACTN1 protein 1-249 amino acids purified from Ecoli. |
| Clone: | PAT1D10AT. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, ELISA, Flow Cytometry |
| Purification Method: | ACTN1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG2b |
| Background: | ACTN1 encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. |
| Synonyms: | ACTN1, Actinin, Alpha 1, Alpha-Actinin Cytoskeletal Isoform, F-Actin Cross-Linking Protein, Non-Muscle Alpha-Actinin-1, BDPLT15, Actinin 1 Smooth Muscle, Alpha-Actinin-1. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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