ACTN1 Monoclonal Antibody [PAT1D10AT] (CPAB0641)

Name: ACTN1 Monoclonal Antibody [PAT1D10AT] (CPAB0641)
SKU: CPAB0641
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Cell Biology Antibodies 2

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Product Name:	ACTN1 Antibody
Product Sku:	CPAB0641
Size:	5μg
Host Species:	Mouse
Immunogen:	Anti-human ACTN1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ACTN1 protein 1-249 amino acids purified from Ecoli.
Clone:	PAT1D10AT.
Reactivity:	Other bodies
Applications:	Western Blot, ELISA, Flow Cytometry

Purification Method:	ACTN1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:	IgG2b
Background:	ACTN1 encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments.
Synonyms:	ACTN1, Actinin, Alpha 1, Alpha-Actinin Cytoskeletal Isoform, F-Actin Cross-Linking Protein, Non-Muscle Alpha-Actinin-1, BDPLT15, Actinin 1 Smooth Muscle, Alpha-Actinin-1.
Storage Buffer:	For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.