ACOX1 Monoclonal Antibody (CAB21217)
- SKU:
- CAB21217
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | ACOX1 Monoclonal Antibody |
| Product Code: | CAB21217 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC53117 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:2000-1:10000, IHC-P 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HepG2, U-251MG, Mouse liver, Mouse kidney, Rat liver |
| Cellular Location: | Peroxisome |
| Customer Validation: | WB(Mus musculus, Homo sapiens) |
The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human ACOX1 (NP_004026.2). |
| Sequence: | MNPDL RRERD SASFN PELLT HILDG SPEKT RRRRE IENMI LNDPD FQHED LNFLT RSQRY EVAVR KSAIM VKKMR EFGIA DPDEI MWFKN FVHRG RPEPL DLHLG MFLPT LLHQA TAEQQ ERFFM PAWNL EIIGT YAQTE MGHGT HLRGL ETTAT YDPET QEFIL NSPTV TSIKW WPGGL GKTSN HAIVL AQLIT KGKCY GLHAF IVPIR EIGTH KPLPG ITVGD IGPKF GYDEI DNGYL KMDNH RIPRE NMLMK YAQVK PDGTY VKPLS |
| Synonyms: | AOX, ACOX, SCOX, MITCH, PALMCOX |
| Calculated MW: | 74kDa |
| Observed MW: | 50kDa/72kDa |
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