Metabolism Recombinant Proteins
ACLY/acly/ATP citrate lyase Recombinant Protein (RPES0749)
- SKU:
- RPES0749
Description
ACLY/acly/ATP citrate lyase Recombinant Protein
ATP citrate lyase is the most important enzyme in many tissues for synthesizing cytosolic acetyl-CoA. The tetramer of ATP citrate lyase/ACLY is composed of identical subunits with a molecular weight of about 440,000. It promotes the conversion of citrate and CoA to acetyl-CoA and oxaloacetate, as well as the transformation of ATP to ADP and phosphate. Acetyl-CoA is involved in a variety of metabolic processes, including lipogenesis and cholesterol synthesis. ATP citrate-lyase may play a role in the formation of acetylcholine in nerve tissue. Trichothiodystrophy 1, Photosensitive, and Trigonitis are all related to ACLY. Transcription Receptor-mediated HIF Regulation and amino acid metabolism are two linked processes to ATP citrate lyase/ACLY.ACLY/acly/ATP citrate lyase Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | ACLY/acly/ATP citrate lyase Recombinant Protein (RPES0749) |
| Product Code: | RPES0749 |
| Size: | 20µg |
| Species: | Human |
| Expressed Host: | Baculovirus-Insect Cells |
| Synonyms: | ACL,ATPCL,CLATP |
| Accession: | P53396 |
| Sequence: | Met 1-Met 1101 |
| Fusion tag: | N-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | A DNA sequence encoding the human ACLY (P53396) (Met 1-Met 1101) was expressed, with a polyhistidine tag at the N-terminus. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 123 kDa |
| AP Mol Mass: | 110 kDa |
| Formulation: | Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.0, 10% gly |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Research Area: |
Metabolism |
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