ZNF821 Antibody (PACO31512)
- SKU:
- PACO31512
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ZNF821 Antibody (PACO31512) |
| Antibody SKU: | PACO31512 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Zinc finger protein 821 protein (1-370AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: ZNF821 antibody at 8µg/ml + MCF-7 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 47, 43 kDa Observed band size: 47 kDa . |
 | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO31512 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO31512 at dilution of 1:100. |
| Background: | May be involved in transcriptional regulation. |
| Synonyms: | Zinc finger protein 821, ZNF821 |
| UniProt Protein Function: | ZNF821: May be involved in transcriptional regulation. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: DNA-binding; C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 16q22.2Cellular Component: nucleusMolecular Function: DNA binding; metal ion bindingBiological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent |
| UniProt Protein Details: | |
| NCBI Summary: | Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene. Mutations in this gene are associated with susceptibility to cerebral infarction. [provided by RefSeq, Sep 2015] |
| UniProt Code: | O75541 |
| NCBI GenInfo Identifier: | 28557781 |
| NCBI Gene ID: | 5583 |
| NCBI Accession: | NP_006246 |
| UniProt Secondary Accession: | O75541,Q16246, Q8NE03, B4DJN5 |
| UniProt Related Accession: | O75541,P24723 |
| Molecular Weight: | 59,521 Da |
| NCBI Full Name: | protein kinase C eta type |
| NCBI Synonym Full Names: | protein kinase C eta |
| NCBI Official Symbol: | PRKCH |
| NCBI Official Synonym Symbols: | PKCL; PKC-L; PRKCL; nPKC-eta |
| NCBI Protein Information: | protein kinase C eta type |
| UniProt Protein Name: | Zinc finger protein 821 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Protein kinase |
| UniProt Gene Name: | ZNF821 |
| UniProt Entry Name: | ZN821_HUMAN |
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