ZNF513 Antibody (PACO31348)
- SKU:
- PACO31348
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ZNF513 Antibody (PACO31348) |
| Antibody SKU: | PACO31348 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Zinc finger protein 513 protein (1-300AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human skin tissue using PACO31348 at dilution of 1:100. |
| Background: | Transcriptional regulator that plays a role in retinal development and maintenance. |
| Synonyms: | Zinc finger protein 513, ZNF513 |
| UniProt Protein Function: | ZNF513: Transcriptional regulator that plays a role in retinal development and maintenance. Defects in ZNF513 are the cause of retinitis pigmentosa type 58 (RP58). A retinal dystrophy belonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. Belongs to the krueppel C2H2-type zinc-finger protein family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 2p23.3Cellular Component: nucleusMolecular Function: DNA binding; protein bindingBiological Process: retina development in camera-type eyeDisease: Retinitis Pigmentosa 58 |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a possible transcriptional regulator involved in retinal development. Defects in this gene can be a cause of autosomal-recessive retinitis pigmentosa. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] |
| UniProt Code: | Q8N8E2 |
| NCBI GenInfo Identifier: | 212276483 |
| NCBI Gene ID: | 130557 |
| NCBI Accession: | Q8N8E2.2 |
| UniProt Secondary Accession: | Q8N8E2,Q3ZCU1, Q68CJ1, Q86UZ3, Q8NDL8, Q96ML3, A8K3S5 B7WP71 |
| UniProt Related Accession: | Q8N8E2 |
| Molecular Weight: | 22,352 Da |
| NCBI Full Name: | Zinc finger protein 513 |
| NCBI Synonym Full Names: | zinc finger protein 513 |
| NCBI Official Symbol: | ZNF513 |
| NCBI Official Synonym Symbols: | RP58; HMFT0656 |
| NCBI Protein Information: | zinc finger protein 513 |
| UniProt Protein Name: | Zinc finger protein 513 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Zinc finger protein |
| UniProt Gene Name: | ZNF513 |
| UniProt Entry Name: | ZN513_HUMAN |
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