ZNF473 Antibody (PACO20951)
- SKU:
- PACO20951
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ZNF473 Antibody (PACO20951) |
| Antibody SKU: | PACO20951 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human ZNF473 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using PACO20951(ZNF473 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO20951(ZNF473 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases. |
| Synonyms: | zinc finger protein 473 |
| UniProt Protein Function: | ZNF473: Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases. Belongs to the krueppel C2H2-type zinc-finger protein family.Protein type: C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 19q13.33Cellular Component: Cajal body; nucleoplasmMolecular Function: protein bindingBiological Process: histone mRNA 3'-end processing; histone mRNA metabolic process; termination of RNA polymerase II transcription |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein, a component of the U7 snRNP complex, plays a role in histone 3'-end pre-mRNA processing and may be required for cell cycle progression to S phase. Expression level and methylation status of this gene may be correlated with bone mineral density. [provided by RefSeq, Jul 2016] |
| UniProt Code: | Q8WTR7 |
| NCBI GenInfo Identifier: | 51702187 |
| NCBI Gene ID: | 25888 |
| NCBI Accession: | Q8WTR7.1 |
| UniProt Secondary Accession: | Q8WTR7,Q9ULS9, Q9Y4Q7, A8K8T7 |
| UniProt Related Accession: | Q8WTR7 |
| Molecular Weight: | 100,182 Da |
| NCBI Full Name: | Zinc finger protein 473 |
| NCBI Synonym Full Names: | zinc finger protein 473 |
| NCBI Official Symbol: | ZNF473 |
| NCBI Official Synonym Symbols: | ZN473; ZFP100 |
| NCBI Protein Information: | zinc finger protein 473 |
| UniProt Protein Name: | Zinc finger protein 473 |
| UniProt Synonym Protein Names: | Zinc finger protein 100 homolog; Zfp-100 |
| Protein Family: | Zinc finger protein |
| UniProt Gene Name: | ZNF473 |
| UniProt Entry Name: | ZN473_HUMAN |
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