Anti-ZNF420 Antibody (PACO22694)

Antibody Name:	ZNF420 Antibody (PACO22694)
Antibody SKU:	PACO22694
Size:	100ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:	Human
Immunogen:	Synthesized peptide derived from internal of human ZNF420.

Form:	Liquid
Storage Buffer:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Western blot analysis of extracts from K562 cells, using ZNF420 antibody.

Background:	May be involved in transcriptional regulation.
Synonyms:	Zinc finger protein 420; ZNF420;

UniProt Protein Function:	ZNF420: May be involved in transcriptional regulation.Protein type: Transcription factor; C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 19q13.12Cellular Component: nucleusMolecular Function: protein binding; DNA binding; metal ion binding; transcription factor activityBiological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
UniProt Protein Details:
NCBI Summary:	The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis. [provided by RefSeq, Jul 2016]
UniProt Code:	Q8TAQ5
NCBI GenInfo Identifier:	22095393
NCBI Gene ID:	147923
NCBI Accession:	NP_653290
UniProt Secondary Accession:	Q8TAQ5
UniProt Related Accession:	Q8TAQ5
Molecular Weight:	80kDa
NCBI Full Name:	zinc finger protein 420 isoform b
NCBI Synonym Full Names:	zinc finger protein 420
NCBI Official Symbol:	ZNF420
NCBI Official Synonym Symbols:	APAK
NCBI Protein Information:	zinc finger protein 420
UniProt Protein Name:	Zinc finger protein 420
UniProt Synonym Protein Names:
Protein Family:	Zinc finger protein
UniProt Gene Name:	ZNF420
UniProt Entry Name:	ZN420_HUMAN