Name: ZNF420 Antibody (PACO20965)
SKU: PACO20965
Availability: OutOfStock

Antibody Name:	ZNF420 Antibody (PACO20965)
Antibody SKU:	PACO20965
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:1000-1:2000, IHC:1:10-1:50
Species Reactivity:	Human
Immunogen:	Synthetic peptide of human ZNF420

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20965(ZNF420 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).

Background:	May be involved in transcriptional regulation.
Synonyms:	zinc finger protein 420

UniProt Protein Function:	ZNF420: May be involved in transcriptional regulation.Protein type: Transcription factor; C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 19q13.12Cellular Component: nucleusMolecular Function: protein binding; DNA binding; metal ion binding; transcription factor activityBiological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
UniProt Protein Details:
NCBI Summary:	The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis. [provided by RefSeq, Jul 2016]
UniProt Code:	Q8TAQ5
NCBI GenInfo Identifier:	22095393
NCBI Gene ID:	147923
NCBI Accession:	NP_653290
UniProt Secondary Accession:	Q8TAQ5
UniProt Related Accession:	Q8TAQ5
Molecular Weight:	80kDa
NCBI Full Name:	zinc finger protein 420 isoform b
NCBI Synonym Full Names:	zinc finger protein 420
NCBI Official Symbol:	ZNF420
NCBI Official Synonym Symbols:	APAK
NCBI Protein Information:	zinc finger protein 420
UniProt Protein Name:	Zinc finger protein 420
UniProt Synonym Protein Names:
Protein Family:	Zinc finger protein
UniProt Gene Name:	ZNF420
UniProt Entry Name:	ZN420_HUMAN