Description
| Antibody Name: | ZNF366 Antibody (PACO31276) |
| Antibody SKU: | PACO31276 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Zinc finger protein 366 protein (455-650AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO31276 at dilution of 1:100. |
![]() | Immunofluorescent analysis of A549 cells using PACO31276 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO31276 at dilution of 1:100. |
| Background: | Has transcriptional repression activity. Acts as corepressor of ESR1; the function seems to involve CTBP1 and histone deacetylases. |
| Synonyms: | Zinc finger protein 366 (Dendritic cell-specific transcript protein) (DC-SCRIPT), ZNF366 |
| UniProt Protein Function: | ZNF366: Has transcriptional repression activity. Acts as corepressor of ESR1; the function seems to involve CTBP1 and histone deacetylases.Protein type: Nuclear receptor co-regulator; C2H2-type zinc finger proteinChromosomal Location of Human Ortholog: 5q13.2|5q13.2Cellular Component: nucleusMolecular Function: estrogen receptor binding; protein binding; transcription corepressor activityBiological Process: negative regulation of estrogen receptor signaling pathway; negative regulation of transcription from RNA polymerase II promoter; response to estrogen stimulus |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8N895 |
| NCBI GenInfo Identifier: | 28380235 |
| NCBI Gene ID: | 167465 |
| NCBI Accession: | Q8N895.1 |
| UniProt Secondary Accession: | Q8N895,Q5HYI9, Q7RTV4 |
| UniProt Related Accession: | Q8N895 |
| Molecular Weight: | 85,107 Da |
| NCBI Full Name: | Zinc finger protein 366 |
| NCBI Synonym Full Names: | zinc finger protein 366 |
| NCBI Official Symbol: | ZNF366 |
| NCBI Official Synonym Symbols: | DCSCRIPT |
| NCBI Protein Information: | zinc finger protein 366 |
| UniProt Protein Name: | Zinc finger protein 366 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Zinc finger protein |
| UniProt Gene Name: | ZNF366 |
| UniProt Entry Name: | ZN366_HUMAN |


