ZNF274 Antibody (PACO39590)
- SKU:
- PACO39590
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ZNF274 Antibody (PACO39590) |
| Antibody SKU: | PACO39590 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Neurotrophin receptor-interacting factor homolog protein (1-320AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO39590 at dilution of 1:100. |
| Background: | Probable transcription repressor. Specifically binds to the 3'-end of zinc-finger coding genes and recruiting chromatin-modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression. |
| Synonyms: | Neurotrophin receptor-interacting factor homolog (Zinc finger protein 274) (Zinc finger protein HFB101) (Zinc finger protein with KRAB and SCAN domains 19) (Zinc finger protein zfp2) (Zf2), ZNF274, ZKSCAN19 |
| UniProt Protein Function: | ZNF274: Probable transcription repressor. Specifically binds to the 3'-end of zinc-finger coding genes and recruiting chromatin- modifying proteins such as SETDB1 and TRIM28/KAP1, leading to transcription repression. Belongs to the krueppel C2H2-type zinc-finger protein family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Nucleolus; DNA-binding; C2H2-type zinc finger protein; Transcription factorChromosomal Location of Human Ortholog: 19qterCellular Component: centrosome; nucleusMolecular Function: neurotrophin p75 receptor binding; protein binding; sequence-specific DNA binding; transcription corepressor activity; transcription factor activityBiological Process: regulation of transcription, DNA-dependent |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a zinc finger protein containing five C2H2-type zinc finger domains, one or two Kruppel-associated box A (KRAB A) domains, and a leucine-rich domain. The encoded protein has been suggested to be a transcriptional repressor. It localizes predominantly to the nucleolus. Alternatively spliced transcript variants encoding different isoforms exist. These variants utilize alternative polyadenylation signals. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96GC6 |
| NCBI GenInfo Identifier: | 327478548 |
| NCBI Gene ID: | 10782 |
| NCBI Accession: | Q96GC6.2 |
| UniProt Secondary Accession: | Q96GC6,Q53XU4, Q6MZG1, Q8WY37, Q8WY38, Q92969, Q9UII0 Q9UII1 |
| UniProt Related Accession: | Q96GC6 |
| Molecular Weight: | 42,448 Da |
| NCBI Full Name: | Neurotrophin receptor-interacting factor homolog |
| NCBI Synonym Full Names: | zinc finger protein 274 |
| NCBI Official Symbol: | ZNF274 |
| NCBI Official Synonym Symbols: | ZF2; HFB101; ZSCAN51; ZKSCAN19 |
| NCBI Protein Information: | neurotrophin receptor-interacting factor homolog |
| UniProt Protein Name: | Neurotrophin receptor-interacting factor homolog |
| UniProt Synonym Protein Names: | Zinc finger protein 274; Zinc finger protein HFB101; Zinc finger protein with KRAB and SCAN domains 19; Zinc finger protein zfp2; Zf2 |
| Protein Family: | Neurotrophin receptor-interacting factor |
| UniProt Gene Name: | ZNF274 |
| UniProt Entry Name: | ZN274_HUMAN |
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