ZNF106 Antibody (PACO20966)
- SKU:
- PACO20966
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ZNF106 Antibody (PACO20966) |
| Antibody SKU: | PACO20966 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:20-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human ZNF106 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20966(ZNF106 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20966(ZNF106 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr¼ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZFP106 (Zinc finger protein 106), also known as zinc finger protein 474, is a 1883 amino acid, human homolog of the mouse Zfp106 protein and is a member of the Kr¼ppel C2H2-type zinc-finger family. Localized to the nucleus, ZFP106 contains two C2H2-type zinc fingers and is thought to be involved in transcriptional regulation. |
| Synonyms: | zinc finger protein 106 |
| UniProt Protein Function: | ZFP106: a protein with six WD40 domains and a zinc-finger domain. May be involved in growth related metabolism. A region of ZFP106 is identical to a 600-amino acid sequence implicated in the insulin receptor signaling pathway. Regulated by NRF-1 and myogenin, and expressed in brown fat, developing brain, and striated muscle.Protein type: C2H2-type zinc finger protein; Nucleolus; Adaptor/scaffoldChromosomal Location of Human Ortholog: 15q15.1Cellular Component: membrane; nucleolus; cytosolMolecular Function: opioid peptide activity; metal ion binding; SH3 domain bindingBiological Process: insulin receptor signaling pathway |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9H2Y7 |
| NCBI GenInfo Identifier: | 546231733 |
| NCBI Gene ID: | 64397 |
| NCBI Accession: | NP_001271235.1 |
| UniProt Secondary Accession: | Q9H2Y7,Q6NSD9, Q6PEK1, Q86T43, Q86T45, Q86T50, Q86T58 Q86TA9, Q96M37, Q9H7B8 |
| UniProt Related Accession: | Q9H2Y7 |
| Molecular Weight: | 122,869 Da |
| NCBI Full Name: | zinc finger protein 106 isoform 2 |
| NCBI Synonym Full Names: | zinc finger protein 106 |
| NCBI Official Symbol: | ZNF106 |
| NCBI Official Synonym Symbols: | SH3BP3; ZFP106; ZNF474 |
| NCBI Protein Information: | zinc finger protein 106; zinc finger protein 474; SH3-domain binding protein 3 |
| UniProt Protein Name: | Zinc finger protein 106 |
| UniProt Synonym Protein Names: | Zinc finger protein 474 |
| Protein Family: | |
| UniProt Gene Name: | ZNF106 |
| UniProt Entry Name: | ZN106_HUMAN |
| Antibodies |
| ZNF106 Antibody (PACO06860) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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