ZMIZ1 Antibody (PACO20335)
- SKU:
- PACO20335
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ZMIZ1 Antibody (PACO20335) |
| Antibody SKU: | PACO20335 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human ZMIZ1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20335(ZMIZ1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 6%SDS-PAGE, Lysate: 40 µg, Lane: Skov3 cells, Primary antibody: PACO20335(ZMIZ1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20335(ZMIZ1 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. |
| Synonyms: | zinc finger, MIZ-type containing 1 |
| UniProt Protein Function: | RAI17: Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressorChromosomal Location of Human Ortholog: 10q22.3Cellular Component: intracellular membrane-bound organelle; nucleoplasm |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010] |
| UniProt Code: | Q9ULJ6 |
| NCBI GenInfo Identifier: | 56404979 |
| NCBI Gene ID: | 57178 |
| NCBI Accession: | Q9ULJ6.3 |
| UniProt Secondary Accession: | Q9ULJ6,Q5JSH9, Q7Z7E6 |
| UniProt Related Accession: | Q9ULJ6 |
| Molecular Weight: | 107,270 Da |
| NCBI Full Name: | Zinc finger MIZ domain-containing protein 1 |
| NCBI Synonym Full Names: | zinc finger MIZ-type containing 1 |
| NCBI Official Symbol: | ZMIZ1 |
| NCBI Official Synonym Symbols: | MIZ; RAI17; ZIMP10; hZIMP10; TRAFIP10 |
| NCBI Protein Information: | zinc finger MIZ domain-containing protein 1 |
| UniProt Protein Name: | Zinc finger MIZ domain-containing protein 1 |
| UniProt Synonym Protein Names: | PIAS-like protein Zimp10; Retinoic acid-induced protein 17 |
| Protein Family: | Zinc finger MIZ domain-containing protein |
| UniProt Gene Name: | ZMIZ1 |
| UniProt Entry Name: | ZMIZ1_HUMAN |
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