ZIC5 Antibody (PACO57380)
- SKU:
- PACO57380
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ZIC5 Antibody (PACO57380) |
| Antibody SKU: | PACO57380 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Zinc finger protein ZIC 5 protein (217-276AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO57380 diluted at 1:200 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA (By similarity). |
| Synonyms: | Zinc finger protein ZIC 5 (Zinc finger protein of the cerebellum 5), ZIC5 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development. Aberrant expression of this gene is seen in medulloblastoma, a childhood brain tumor. This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. This gene encodes a transcription factor that can bind and transactivate the apolipoprotein E gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q96T25 |
| NCBI GenInfo Identifier: | 22547182 |
| NCBI Gene ID: | 7545 |
| NCBI Accession: | NP_003403.2 |
| UniProt Secondary Accession: | Q96T25,O95409, O60481, Q8N9L1, Q96T25 |
| UniProt Related Accession: | Q96T25,Q15915 |
| Molecular Weight: | |
| NCBI Full Name: | zinc finger protein ZIC 1 |
| NCBI Synonym Full Names: | Zic family member 1 |
| NCBI Official Symbol: | ZIC1 |
| NCBI Official Synonym Symbols: | ZIC; CRS6; ZNF201 |
| NCBI Protein Information: | zinc finger protein ZIC 1 |
| UniProt Protein Name: | Zinc finger protein ZIC 1 |
| UniProt Synonym Protein Names: | Zinc finger protein 201; Zinc finger protein of the cerebellum 1 |
| Protein Family: | |
| UniProt Gene Name: | ZIC1 |
| UniProt Entry Name: | ZIC1_HUMAN |
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