ZFP36L2 Antibody (PACO20705)
- SKU:
- PACO20705
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ZFP36L2 Antibody (PACO20705) |
| Antibody SKU: | PACO20705 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human ZFP36L2 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20705(ZFP36L2 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO20705(ZFP36L2 Antibody) at dilution 1/45, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. |
| Synonyms: | ZFP36 ring finger protein-like 2 |
| UniProt Protein Function: | ZFP36L2: Probable regulatory protein involved in regulating the response to growth factors. RNA-binding protein that binds to 5'UUAUUUAUUU-3' core sequence. Binds to the class II AU-rich element (ARE) in the 3'-UTR of target mRNAs and promotes their deadenylation and degradation. |
| UniProt Protein Details: | Protein type:Transcription factor Chromosomal Location of Human Ortholog: 2p22.3-p21 Cellular Component: cytoplasm; nucleus Molecular Function:AU-rich element binding; transcription factor activity Biological Process: cell proliferation; hemopoiesis; mRNA catabolic process; somatic stem cell division; somatic stem cell maintenance |
| NCBI Summary: | This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P47974 |
| NCBI GenInfo Identifier: | 146291085 |
| NCBI Gene ID: | 678 |
| NCBI Accession: | P47974.3 |
| UniProt Secondary Accession: | P47974,Q53TB4, Q9BSJ3, |
| UniProt Related Accession: | P47974 |
| Molecular Weight: | 51,063 Da |
| NCBI Full Name: | Zinc finger protein 36, C3H1 type-like 2 |
| NCBI Synonym Full Names: | ZFP36 ring finger protein like 2 |
| NCBI Official Symbol: | ZFP36L2 |
| NCBI Official Synonym Symbols: | BRF2; ERF2; ERF-2; TIS11D; RNF162C |
| NCBI Protein Information: | zinc finger protein 36, C3H1 type-like 2 |
| UniProt Protein Name: | Zinc finger protein 36, C3H1 type-like 2 |
| UniProt Synonym Protein Names: | Butyrate response factor 2; EGF-response factor 2; ERF-2; Protein TIS11D |
| Protein Family: | mRNA decay activator protein |
| UniProt Gene Name: | ZFP36L2 |
| UniProt Entry Name: | TISD_HUMAN |
| Antibodies | ELISA Kits |
| ZFP36L2 Antibody (PACO01632) | TISD Colorimetric Cell-Based ELISA |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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