Description
Antibody Name: | ZFP36L2 Antibody (PACO13301) |
Antibody SKU: | PACO13301 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human ZFP36L2 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | zinc finger protein 36, C3H type-like 2;ZFP36L2;BRF2;ERF-2;ERF2;RNF162C;TIS11D ; |
UniProt Protein Function: | ZFP36L2: Probable regulatory protein involved in regulating the response to growth factors. RNA-binding protein that binds to 5'UUAUUUAUUU-3' core sequence. Binds to the class II AU-rich element (ARE) in the 3'-UTR of target mRNAs and promotes their deadenylation and degradation. |
UniProt Protein Details: | Protein type:Transcription factor Chromosomal Location of Human Ortholog: 2p22.3-p21 Cellular Component: cytoplasm; nucleus Molecular Function:AU-rich element binding; transcription factor activity Biological Process: cell proliferation; hemopoiesis; mRNA catabolic process; somatic stem cell division; somatic stem cell maintenance |
NCBI Summary: | This gene is a member of the TIS11 family of early response genes. Family members are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. [provided by RefSeq, Jul 2008] |
UniProt Code: | P47974 |
NCBI GenInfo Identifier: | 146291085 |
NCBI Gene ID: | 678 |
NCBI Accession: | P47974.3 |
UniProt Secondary Accession: | P47974,Q53TB4, Q9BSJ3, |
UniProt Related Accession: | P47974 |
Molecular Weight: | 51,063 Da |
NCBI Full Name: | Zinc finger protein 36, C3H1 type-like 2 |
NCBI Synonym Full Names: | ZFP36 ring finger protein like 2 |
NCBI Official Symbol: | ZFP36L2 |
NCBI Official Synonym Symbols: | BRF2; ERF2; ERF-2; TIS11D; RNF162C |
NCBI Protein Information: | zinc finger protein 36, C3H1 type-like 2 |
UniProt Protein Name: | Zinc finger protein 36, C3H1 type-like 2 |
UniProt Synonym Protein Names: | Butyrate response factor 2; EGF-response factor 2; ERF-2; Protein TIS11D |
Protein Family: | mRNA decay activator protein |
UniProt Gene Name: | ZFP36L2 |
UniProt Entry Name: | TISD_HUMAN |