Antibody Name:	ZFAND6 Antibody (PACO52446)
Antibody SKU:	PACO52446
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, IHC, IF
Recommended Dilutions:	ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200
Species Reactivity:	Human
Immunogen:	Recombinant Human AN1-type zinc finger protein 6 protein (1-208AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Immunohistochemistry of paraffin-embedded human liver tissue using PACO52446 at dilution of 1:100.
	Immunofluorescent analysis of A549 cells using PACO52446 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Background:

Involved in regulation of TNF-α induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity).

Synonyms:

AN1-type zinc finger protein 6 (Associated with PRK1 protein) (Zinc finger A20 domain-containing protein 3), ZFAND6, AWP1 ZA20D3

UniProt Protein Function:	Za20d3: Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'- linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Unknown function Chromosomal Location of Human Ortholog: 15q25.1 Cellular Component: cytoplasm Molecular Function:protein binding; DNA binding; zinc ion binding; polyubiquitin binding Biological Process: apoptosis; protein targeting to peroxisome; regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of apoptosis
UniProt Code:	Q6FIF0
NCBI GenInfo Identifier:	339276069
NCBI Gene ID:	54469
NCBI Accession:	NP_001229844.1
UniProt Secondary Accession:	Q6FIF0,O95792, Q9BQF7, Q9GZY3, D3DW92, D3DW94,
UniProt Related Accession:	Q6FIF0
Molecular Weight:	21,396 Da
NCBI Full Name:	AN1-type zinc finger protein 6 isoform a
NCBI Synonym Full Names:	zinc finger, AN1-type domain 6
NCBI Official Symbol:	ZFAND6
NCBI Official Synonym Symbols:	AWP1; ZA20D3; ZFAND5B
NCBI Protein Information:	AN1-type zinc finger protein 6; protein associated with PRK1; zinc finger, A20 domain containing 3
UniProt Protein Name:	AN1-type zinc finger protein 6
UniProt Synonym Protein Names:	Associated with PRK1 protein; Zinc finger A20 domain-containing protein 3
Protein Family:	AN1-type zinc finger protein
UniProt Gene Name:	ZFAND6
UniProt Entry Name:	ZFAN6_HUMAN